Anti-Murine IL-1β 0 ReviewsSubmit a Review Product Details Catalog Number: 500-P51 Description: Source: Polyclonal Rabbit Preparation: Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant mIL-1β. Anti-Murine IL-1β specific antibody was purified by affinity chromatography employing immobilized mIL-1β matrix. Immunogen: E.coli derived Recombinant Murine IL-1β (PeproTech catalog# 211-11B) Sandwich ELISA: To detect mIL-1β by sandwich ELISA (using 100 μl/well antibody solution) a concentration of 0.5 - 2.0 μg/ml of this antibody is required. This antigen affinity purified antibody, in conjunction with PeproTech’s Biotinylated Anti-Murine IL-1β (500-P51Bt) as a detection antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant mIL-1β. Western Blot: To detect mIL-1β by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 µg/ml. Used in conjunction with compatible secondary reagents the detection limit for recombinant mIL-1β is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions. Note: Additional applications tested on a lot-to-lot basis. Please contact Technical Support for more information. Cross Reactivity Cited in References: Human, Mouse, Mouse + Bacteria References SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest COVID-19 Angiogenesis/Cardiovascular Cancer Diabetes/Weight Regulation Immune System Inflammation Neurobiology Proliferation Stem Cells & Differentiation Wound Healing Allergy Transplantation Recent Citations First Author Lopez-Rodriguez, A B Title Acute systemic inflammation exacerbates neuroinflammation in Alzheimer's disease: IL-1β drives amplified responses in primed astrocytes and neuronal network dysfunction. Citation Alzheimer's &Amp; Dementia : The Journal Of The Alzheimer's Association; 17(10) pg1735-1755 PubMed ID 34080771 First Author Klooster, J P Title Enterocytes, fibroblasts and myeloid cells synergize in anti-bacterial and anti-viral pathways with IL22 as the central cytokine Citation Communications Biology; 4(1) pg631 PubMed ID 34045640 First Author Srivastava, S P Title Loss of endothelial glucocorticoid receptor accelerates diabetic nephropathy Citation Nature Communications; 12(1) pg2368 PubMed ID 33888696
