Recombinant Human Apo-SAA1 0 ReviewsSubmit a Review Product Details Catalog Number: 300-53 Description: Serum amyloid A proteins (SAA) represents a family of apolipoproteins that circulates in association with high-density lipoproteins (HDL). The level of Apo-SAA, normally 1-5 μg/ml in plasma, increases 500-1000 fold within 24 hours of an inflammatory stimulus and, under these conditions, is the most abundant HDL apolipoprotein. The human SAA gene codes for a 122 amino acid nonglycosylated polypeptide, which contains an 18 amino acid N-terminal sequence. Recombinant Human Apo-SAA1 is an 11.7 kDa protein containing 105 amino acid residues. Source: E.coli Synonyms: Serum amyloid A-1 protein AA Sequence: MRSFFSFLGE AFDGARDMWR AYSDMREANY IGSDKYFHAR GNYDAAKRGP GGVWAAEAIS DARENIQRFF GHGAEDSLAD QAANEWGRSG KDPNHFRPAG LPEKY Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human monocytes using a concentration range of 10.0-100.0 ng/ml. Calculated Molecular Weight: 11.7 kDa Accession Number: P0DJI8 Gene ID: 6288 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) Note: 1mg will be provided as 2x500μg. Cross Reactivity Cited in References: Human, Mouse, Virus References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Angiogenesis/Cardiovascular Immune System Inflammation Recent Citations First Author White, M R Title Effects of serum amyloid protein A on influenza A virus replication and viral interactions with neutrophils. Citation Journal of Leukocyte Biology; 110(1) pg155-166 PubMed ID 33205458 First Author Klooster, J P Title Enterocytes, fibroblasts and myeloid cells synergize in anti-bacterial and anti-viral pathways with IL22 as the central cytokine Citation Communications Biology; 4(1) pg631 PubMed ID 34045640 First Author Getachew, A Title SAA1/TLR2 axis directs chemotactic migration of hepatic stellate cells responding to injury. Citation Iscience; 24(5) pg102483 PubMed ID 34113824
