Recombinant Human FGF-16 1 ReviewsSubmit a Review Product Details Catalog Number: 100-29 Description: FGF-16 is a heparin-binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-16 signals through FGFR 2c and 3c. FGF-16 plays a role in the development of the central nervous system. Recombinant Human FGF-16 is a 23.6 kDa protein consisting of 206 amino acid residues. Source: E.coli Synonyms: Fibroblast Growth Factor-16, FGFG AA Sequence: AEVGGVFASL DWDLHGFSSS LGNVPLADSP GFLNERLGQI EGKLQRGSPT DFAHLKGILR RRQLYCRTGF HLEIFPNGTV HGTRHDHSRF GILEFISLAV GLISIRGVDS GLYLGMNERG ELYGSKKLTR ECVFREQFEE NWYNTYASTL YKHSDSERQY YVALNKDGSP REGYRTKRHQ KFTHFLPRPV DPSKLPSMSR DLFHYR Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors. The expected ED50 is ≤ 0.5 ng/ml corresponding to a specific activity of ≥ 2 x 106 units/mg. Calculated Molecular Weight: 23.6 kDa Accession Number: O43320 Gene ID: 8823 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) Note: 250μg is the largest vial size for this product. Larger sizes supplied as multiple 250μg vials. Cross Reactivity Cited in References: Human, Mouse, Rat References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Angiogenesis/Cardiovascular Bone, Skeletal, Cartilage Cancer FGF Superfamily Immune System Inflammation Neurobiology Stem Cells & Differentiation Wound Healing Recent Citations First Author Savchenko, E Title FGF family members differentially regulate maturation and proliferation of stem cell-derived astrocytes. Citation Scientific Reports; 9(1) pg9610 PubMed ID 31270389 First Author Westphal, S Title Fibroblast growth factor 8b induces uncoupling protein 1 expression in epididymal white preadipocytes. Citation Scientific Reports; 9(1) pg8470 PubMed ID 31186471 First Author Duan, Y Title Fibroblast growth factor 16 stimulates proliferation but blocks differentiation of rat stem Leydig cells during regeneration. Citation Journal of Cellular and Molecular Medicine; 23(4) pg2632-2644 PubMed ID 30672118 Product Reviews Existing reviews Recombinant human FGF-16 for primary rat cardiomyocyte cultures Used 100ng/ml concentration on neonatal rat cardiomyocytes with and without FBS in DMEM medium. Able to show binding affinity to FGF-16 receptors and subcellular signaling pathway activation. Great product. From: Jie | Date: 8/27/2020 × Recombinant human FGF-16 for primary rat cardiomyocyte cultures Used 100ng/ml concentration on neonatal rat cardiomyocytes with and without FBS in DMEM medium. Able to show binding affinity to FGF-16 receptors and subcellular signaling pathway activation. Great product. From: Jie | Date: 8/27/2020 Close
