Recombinant Human FGF-19 0 ReviewsSubmit a Review Product Details Catalog Number: 100-32 Description: The FGF family plays central roles during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-19, a member of the FGF family, is a high-affinity heparin-dependent ligand for FGFR4. FGF-19 is expressed during brain development and embryogenesis. Recombinant Human FGF-19 is a 21.8 kDa protein containing 195 amino acid residues. Source: E.coli Synonyms: Fibroblast Growth Factor-19, FGFJ AA Sequence: MRPLAFSDAG PHVHYGWGDP IRLRHLYTSG PHGLSSCFLR IRADGVVDCA RGQSAHSLLE IKAVALRTVA IKGVHSVRYL CMGADGKMQG LLQYSEEDCA FEEEIRPDGY NVYRSEKHRL PVSLSSAKQR QLYKNRGFLP LSHFLPMLPM VPEEPEDLRG HLESDMFSSP LETDSMDPFG LVTGLEAVRS PSFEK Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by a cell proliferation assay using balb/c 3T3 cells. The expected ED50 for this effect is 100-150 ng/ml. Calculated Molecular Weight: 21.8 kDa Accession Number: O95750 Gene ID: 9965 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) Note: 1mg will be provided as 2x500μg. Cross Reactivity Cited in References: Chicken, Hamster, Human, Mouse References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Angiogenesis/Cardiovascular Bone, Skeletal, Cartilage Cancer FGF Superfamily Immune System Inflammation Neurobiology Stem Cells & Differentiation Wound Healing Recent Citations First Author Nguyen, V V Title A human kidney and liver organoid-based multi-organ-on-a-chip model to study the therapeutic effects and biodistribution of mesenchymal stromal cell-derived extracellular vesicles. Citation Journal Of Extracellular Vesicles; 11(11) pge12280 PubMed ID 36382606 First Author Li, P Title Recapitulating hepatitis E virus-host interactions and facilitating antiviral drug discovery in human liver-derived organoids. Citation Science Advances; 8(3) pgeabj5908 PubMed ID 35044825 First Author Clark, M P Title Clinical stage drugs targeting inhibitor of apoptosis proteins purge episomal Hepatitis B viral genome in preclinical models Citation Cell Death & Disease; 12(7) pg641 PubMed ID 34162831
