Recombinant Human IL-8 (CXCL8) (72 a.a.) 0 ReviewsSubmit a Review Product Details Catalog Number: 200-08M Description: IL-8 is a proinflammatory CXC chemokine that can signal through the CXCR1 and CXCR2 receptors. It is secreted by monocytes and endothelial cells. IL-8 chemoattracts and activates neutrophils. Recombinant Human IL-8 (monocyte-derived) is an 8.4 kDa protein containing 72 amino acid residues. Source: E.coli Synonyms: CXCL8, monocyte-derived neutrophil chemotactic factor (MDNCF), neutrophil activating factor (NAF), NAP-1 AA Sequence: SAKELRCQCI KTYSKPFHPK FIKELRVIES GPHCANTEII VKLSDGRELC LDPKENWVQR VVEKFLKRAE NS Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human peripheral blood neutrophils using a concentration range of 10.0-100.0 ng/ml. Calculated Molecular Weight: 8.4 kDa Accession Number: P10145 Gene ID: 3576 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) Cross Reactivity Cited in References: Bacteria, Human, Human + Rat, Monkey, Mouse, Rat References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest COVID-19 Angiogenesis/Cardiovascular Apoptosis Chemotaxis Immune System Inflammation Neurobiology Wound Healing Allergy Transplantation Recent Citations First Author Cai, B Title N2-Polarized Neutrophils Guide Bone Mesenchymal Stem Cell Recruitment and Initiate Bone Regeneration: A Missing Piece of the Bone Regeneration Puzzle. Citation Advanced science (Weinheim, Baden-Wurttemberg, Germany); 8(19) pge2100584 PubMed ID 34382372 First Author Arif, N Title PECAM-1 supports leukocyte diapedesis by tension-dependent dephosphorylation of VE-cadherin. Citation The EMBO Journal; 40(9) pge106113 PubMed ID 33604918 First Author Miao, L Title FABP4 deactivates NF-κB-IL1α pathway by ubiquitinating ATPB in tumor-associated macrophages and promotes neuroblastoma progression. Citation Clinical And Translational Medicine; 11(4) pge395 PubMed ID 33931964
