Recombinant Human IL-8 (CXCL8) (77 a.a.) 0 ReviewsSubmit a Review Product Details Catalog Number: 200-08 Description: IL-8 is a proinflammatory CXC chemokine that can signal through the CXCR1 and CXCR2 receptors. It is secreted by monocytes and endothelial cells. IL-8 chemoattracts and activates neutrophils. Recombinant Human IL-8 (CXCL8) (77 a.a.) (endothelial-derived) is an 8.9 kDa protein containing 77 amino acid residues. Source: E.coli Synonyms: Interleukin-8, CXCL8, monocyte-derived neutrophil chemotactic factor (MDNCF), neutrophil activating factor (NAF), NAP-1 AA Sequence: AVLPRSAKEL RCQCIKTYSK PFHPKFIKEL RVIESGPHCA NTEIIVKLSD GRELCLDPKE NWVQRVVEKF LKRAENS Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human peripheral blood neutrophils using a concentration range of 25.0-150.0 ng/ml. Calculated Molecular Weight: 8.9 kDa Accession Number: P10145 Gene ID: 3576 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) Cross Reactivity Cited in References: Bacteria, Chicken, Human, Mouse, Pig References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest COVID-19 Angiogenesis/Cardiovascular Apoptosis Chemotaxis Immune System Inflammation Neurobiology Wound Healing Allergy Transplantation Recent Citations First Author Jain, P Title Reconstruction of Ultra-thin Alveolar-capillary Basement Membrane Mimics. Citation Advanced Biology; 5(8) pge2000427 PubMed ID 33987968 First Author Wang, W Title Stromal induction of BRD4 phosphorylation Results in Chromatin Remodeling and BET inhibitor Resistance in Colorectal Cancer Citation Nature Communications; 12(1) pg4441 PubMed ID 34290255 First Author Ocaña-Guzmán, R Title Leukocytes from Patients with Drug-Sensitive and Multidrug-Resistant Tuberculosis Exhibit Distinctive Profiles of Chemokine Receptor Expression and Migration Capacity. Citation Journal Of Immunology Research; 2021 pg6654220 PubMed ID 33977111
