Recombinant Human KGF (FGF-7) 3 ReviewsSubmit a Review Product Details Catalog Number: 100-19 Description: KGF (FGF-7) is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth, and the regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. KGF (FGF-7) is a mitogen factor specific for epithelial cells and keratinocytes. KGF (FGF-7) signals through FGFR 2b. KGF (FGF-7) plays a role in kidney and lung development, as well as in angiogenesis and wound healing. Recombinant Human KGF (FGF-7) is an 18.9 kDa protein consisting of 163 amino acid residues. Source: E.coli Synonyms: Keratinocyte Growth Factor, Fibroblast Growth Factor-7, HBGF-7 AA Sequence: CNDMTPEQMA TNVNCSSPER HTRSYDYMEG GDIRVRRLFC RTQWYLRIDK RGKVKGTQEM KNNYNIMEIR TVAVGIVAIK GVESEFYLAM NKEGKLYAKK ECNEDCNFKE LILENHYNTY ASAKWTHNGG EMFVALNQKG IPVRGKKTKK EQKTAHFLPM AIT Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by a cell proliferation assay using 4MBr-5 cells. The expected ED50 for this effect is 0.1-15 ng/ml. This product has been tested against the WHO standard. International Unit information can be found here. Calculated Molecular Weight: 18.9 kDa Accession Number: P21781 Gene ID: 2252 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) Cross Reactivity Cited in References: Human, Leech, Mouse, Rat References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Angiogenesis/Cardiovascular FGF Superfamily Immune System Stem Cells & Differentiation Wound Healing Diabetes/Weight Regulation Recent Citations First Author Tanaka, J Title Human induced pluripotent stem cell-derived salivary gland organoids model SARS-CoV-2 infection and replication. Citation Nature Cell Biology; 24(11) pg1595-1605 PubMed ID 36253535 First Author Ngan, S Y Title Stage-Specific Generation of Human Pluripotent Stem Cell Derived Lung Models to Measure CFTR Function. Citation Current Protocols; 2(1) pge341 PubMed ID 35025140 First Author van der Vaart, J Title Modelling of primary ciliary dyskinesia using patient-derived airway organoids. Citation EMBO reports; 22(12) pge52058 PubMed ID 34693619 Product Reviews Existing reviews It works well It works well both in human and mouse organoid culture. From: Eun Joo | Date: 7/8/2020 × It works well It works well both in human and mouse organoid culture. From: Eun Joo | Date: 7/8/2020 Close Excellent quality We utilize FGF7 as part of lung cancer organoid media for cancers which do not have EGFR mutations. We have had great results and excellent service. From: Dora | Date: 7/24/2020 × Excellent quality We utilize FGF7 as part of lung cancer organoid media for cancers which do not have EGFR mutations. We have had great results and excellent service. From: Dora | Date: 7/24/2020 Close Great for organoids! We use this in two types patient tumor organoid media and have wonderful results in each. From: Julie-Ann | Date: 8/3/2021 × Great for organoids! We use this in two types patient tumor organoid media and have wonderful results in each. From: Julie-Ann | Date: 8/3/2021 Close
