Recombinant Human TGF-α 1 ReviewsSubmit a Review Product Details Catalog Number: 100-16A Description: TGF-α is an EGF-related polypeptide growth factor that signals through the EGF receptor, and stimulates the proliferation of a wide range of epidermal and epithelial cells. It is produced by monocytes, keratinocytes, and various tumor cells. TGF-α induces anchorage-independence transformation in cultured cells. Human, murine and rat TGF-α are cross-species reactive. Recombinant Human TGF-α is a 50 amino acid polypeptide (5.5 kDa) which shares approximately 40% sequence homology with EGF, including 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds. Source: E.coli Synonyms: Transforming Growth Factor-α, Sacroma growth factor, TGF-type I, ETGF AA Sequence: VVSHFNDCPD SHTQFCFHGT CRFLVQEDKP ACVCHSGYVG ARCEHADLLA Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BALB/c 3T3 cells is ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 106 units/mg. Calculated Molecular Weight: 5.5 kDa Accession Number: P01135 Gene ID: 7039 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) Cross Reactivity Cited in References: Chicken, Horse, Human, Mouse, Rat References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Angiogenesis/Cardiovascular Cancer Immune System Inflammation Neurobiology Stem Cells & Differentiation Wound Healing Recent Citations First Author Yang, Q Title FOXM1 regulates glycolysis in nasopharyngeal carcinoma cells through PDK1. Citation Journal of Cellular and Molecular Medicine; 26(13) pg3783-3796 PubMed ID 35656815 First Author Zhang, B Title A new protocol for long-term culture of a specific subpopulation of liver cancer stem cells enriched by cell surface markers. Citation FEBS Open Bio; 10(9) pg1737-1747 PubMed ID 32662250 First Author Lundby, A Title Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites. Citation Cell; 179(2) pg543-560.e26 PubMed ID 31585087 Product Reviews Existing reviews High quality and better price This product worked well for my project. The price is reasonable and lower than most of vendors. From: Jin | Date: 8/26/2020 × High quality and better price This product worked well for my project. The price is reasonable and lower than most of vendors. From: Jin | Date: 8/26/2020 Close
