Recombinant Murine FGF-acidic 0 ReviewsSubmit a Review Product Details Catalog Number: 450-33A Description: FGF-acidic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-acidic is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. FGF-acidic has the ability to signal through all the FGF receptors. Recombinant Murine FGF-acidic is a 15.9 kDa protein consisting of 141 amino acid residues. Source: E.coli Synonyms: Fibroblast Growth Factor-acidic, FGF-1, HBGF-1, ECGF-beta AA Sequence: MFNLPLGNYK KPKLLYCSNG GHFLRILPDG TVDGTRDRSD QHIQLQLSAE SAGEVYIKGT ETGQYLAMDT EGLLYGSQTP NEECLFLERL EENHYNTYTS KKHAEKNWFV GLKKNGSCKR GPRTHYGQKA ILFLPLPVSS D Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by a cell proliferation assay using Balb/c 3T3 cells. The expected ED50 is ≤ 0.2 ng/ml in the presence of 10 µg/ml heparin, corresponding to a specific activity of ≥ 5 x 106 units/mg. Calculated Molecular Weight: 15.9 kDa Accession Number: P61148 Gene ID: 14164 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) Cross Reactivity Cited in References: Human, Mouse, References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Angiogenesis/Cardiovascular Bone, Skeletal, Cartilage Cancer Cell Culture FGF Superfamily Immune System Inflammation Neurobiology Stem Cells & Differentiation Wound Healing Recent Citations First Author Guccini, I Title Senescence Reprogramming by TIMP1 Deficiency Promotes Prostate Cancer Metastasis. Citation Cancer Cell; 39(1) pg68-82.e9 PubMed ID 33186519 First Author Westphal, S Title Fibroblast growth factor 8b induces uncoupling protein 1 expression in epididymal white preadipocytes. Citation Scientific Reports; 9(1) pg8470 PubMed ID 31186471 First Author Ishihara, J Title Laminin heparin-binding peptides bind to several growth factors and enhance diabetic wound healing. Citation Nature Communications; 9(1) pg2163 PubMed ID 29867149
