Recombinant Rat GRO-β/MIP-2 (CXCL2)

Product Details

Catalog Number: 400-11

Description:

All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant Rat GRO-β/MIP-2 is a 7.9 kDa protein consisting of 73 amino acids, including the 'ELR' motif common to the CXC chemokine family that binds to CXCR1 or CXCR2.

Source: E.coli

Synonyms: Growth Regulated Protein/Melanoma Growth Stimulatory Activity (MGSAβ), CXCL2, Macrophage Inflammatory Protein-2, MIP-2α, GRO2

AA Sequence: VVVASELRCQ CLTTLPRVDF KNIQSLTVTP PGPHCAQTEV IATLKDGHEV CLNPEAPLVQ RIVQKILNKG KAN

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract rat neutrophils using a concentration range of 10.0-100.0 ng/ml.

Calculated Molecular Weight: 7.9 kDa

Accession Number: P30348

Gene ID: 114105

Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)

Cross Reactivity Cited in References:

Human, Mouse, Rat

Country Of Origin: USA

Not for human use.

Research Interest

Angiogenesis/Cardiovascular

Recent Citations

First Author

Abu-Taha, M

Title

Menopause and ovariectomy cause a low grade of systemic inflammation that may be prevented by chronic treatment with low doses of estrogen or losartan.

Citation

Journal of immunology (Baltimore, Md. : 1950); 183(2) pg1393-402

PubMed ID

19553526

First Author

Mateo, T

Title

A critical role for TNFalpha in the selective attachment of mononuclear leukocytes to angiotensin-II-stimulated arterioles.

Citation

Blood; 110(6) pg1895-902

PubMed ID

17595330

First Author

Burdon, P C

Title

The CXC chemokine MIP-2 stimulates neutrophil mobilization from the rat bone marrow in a CD49d-dependent manner.

Citation

Blood; 105(6) pg2543-8

PubMed ID

15542579

Chemokines