Recombinant Viral MIP-2 0 ReviewsSubmit a Review Product Details Catalog Number: 350-03 Description: Viral MIP-2 (vMIP-2) is a chemokine analog encoded by the human herpes virus, and has been shown to have antagonist activity towards several chemokine receptors. Recombinant Viral MIP-2 is a 7.9 kDa protein consisting of 70 amino acids, including the four highly conserved cysteine residues present in CC chemokines. Source: E.coli Synonyms: Macrophage Inflammatory Protein-2 AA Sequence: LGASWHRPDK CCLGYQKRPL PQVLLSSWYP TSQLCSKPGV IFLTKRGRQV CADKSKDWVK KLMQQLPVTA Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by the inhibitory effect on monocyte migration response to human MIP-1 alpha using a concentration range of 1.0µg-10.0µg/ml of viral MIP-2 will inhibit 25ng/ml of human MIP-1 alpha. Calculated Molecular Weight: 7.9 kDa Accession Number: Q98157 Gene ID: 4961514 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) Cross Reactivity Cited in References: Human, Mouse References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Angiogenesis/Cardiovascular Chemotaxis Immune System Inflammation Neurobiology Wound Healing Recent Citations First Author Yu, J Title Generation of an osteoblast-based artificial niche that supports in vitro B lymphopoiesis. Citation Experimental & molecular medicine; 49(11) pge400 PubMed ID 29170473 First Author Kovács, M Title The Src family kinases Hck, Fgr, and Lyn are critical for the generation of the in vivo inflammatory environment without a direct role in leukocyte recruitment. Citation The Journal of Experimental Medicine; 211(10) pg1993-2011 PubMed ID 25225462 First Author Singh, U P Title Viral macrophage-inflammatory protein-II: a viral chemokine that differentially affects adaptive mucosal immunity compared with its mammalian counterparts. Citation Journal of immunology (Baltimore, Md. : 1950); 173(9) pg5509-16 PubMed ID 15494499
