Anti-Human sRANK Ligand (Polyclonal Rabbit) 0 BewertungenSubmit a Review Produktdetails Katalognummer: 500-P133 Beschreibung: Source: Polyclonal Rabbit Preparation: Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant hsRANKL. Anti-Human sRANKL specific antibody was purified by affinity chromatography employing immobilized hsRANKL matrix. Immunogen: E.coli derived Recombinant Human sRANK Ligand (PeproTech catalog# 310-01) Sandwich ELISA: To detect hsRANKL by sandwich ELISA (using 100 μl/well antibody solution) a concentration of 0.5 - 2.0 μg/ml of this antibody is required. This antigen affinity purified antibody, in conjunction with PeproTech’s Biotinylated Anti-Human sRANKL (500-P133Bt) as a detection antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant hsRANKL. Western Blot: To detect hsRANKL by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 µg/ml. Used in conjunction with compatible secondary reagents the detection limit for recombinant hsRANKL is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions. Note: Additional applications tested on a lot-to-lot basis. Please contact Technical Support for more information. crossreactivity: Human, Mouse References SDS Datenblattsuche Product Line Country Of Origin: USA Not for human use. Research Interest Apoptosis Bone, Skeletal, Cartilage Immune System TNF Superfamily product.subtitle.recentcitations Erstautor Martínez-Calatrava, M J Titel RANKL synthesized by articular chondrocytes contributes to juxta-articular bone loss in chronic arthritis. Literaturstelle Arthritis research & therapy; 14(3) pgR149 PubMed ID 22709525 Erstautor Ivanovska, N Titel Bone resorption and remodeling in murine collagenase-induced osteoarthritis after administration of glucosamine. Literaturstelle Arthritis research & therapy; 13(2) pgR44 PubMed ID 21410959 Erstautor Baud'huin, M Titel Factor VIII-von Willebrand factor complex inhibits osteoclastogenesis and controls cell survival. Literaturstelle The Journal of Biological Chemistry; 284(46) pg31704-13 PubMed ID 19758994