Recombinant Murine FGF-basic

Produktdetails

Katalognummer: 450-33

Beschreibung:

FGF-basic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-basic is a non-glycosylated, heparin-binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland, liver, monocytes, epithelial cells and endothelial cells. FGF-basic signals through FGFR 1b, 1c, 2c, 3c and 4. Recombinant Murine FGF-basic is a 16.3 kDa protein consisting of 145 amino acid residues.

Source: E.coli

Synonyms: Fibroblast Growth Factor-basic, FGF-2, HBGF-2, Prostatropin

AA Sequence: PALPEDGGAA FPPGHFKDPK RLYCKNGGFF LRIHPDGRVD GVREKSDPHV KLQLQAEERG VVSIKGVCAN RYLAMKEDGR LLASKCVTEE CFFFERLESN NYNTYRSRKY SSWYVALKRT GQYKLGSKTG PGQKAILFLP MSAKS

Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by a cell proliferation assay using Balb/c 3T3 cells. The expected ED₅₀ is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁶ units/mg.

Calculated Molecular Weight: 16.3 kDa

Accession Number: P15655

Gene ID: 14173

Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)

Note:

1mg will be provided as 2x500μg.

crossreactivity:

Human, Mouse, Rabbit, Rat

Country Of Origin: USA

Not for human use.

Research Interest

Organoids

Angiogenesis/Cardiovascular

Bone, Skeletal, Cartilage

Stem Cells & Differentiation

Wound Healing

Diabetes/Weight Regulation

product.subtitle.recentcitations

Erstautor

Sakuma, R

Titel

Brain Pericytes Acquire Stemness via the Nrf2-Dependent Antioxidant System.

Literaturstelle

Stem cells (Dayton, Ohio); 40(7) pg641-654

PubMed ID

35353891

Erstautor

Yoon, Y

Titel

Salivary gland organoid culture maintains distinct glandular properties of murine and human major salivary glands.

Literaturstelle

Nature Communications; 13(1) pg3291

PubMed ID

35672412

Erstautor

Fan, L

Titel

Exosomes-Loaded Electroconductive Hydrogel Synergistically Promotes Tissue Repair after Spinal Cord Injury via Immunoregulation and Enhancement of Myelinated Axon Growth.

Literaturstelle

Advanced science (Weinheim, Baden-Wurttemberg, Germany); 9(13) pge2105586

PubMed ID

35253394

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Vorliegende Bewertungen

Perfect for mouse neural stem cells

We use recombinant murine FGF to maintain mouse neural stem cells. Quite important for the primary neural stem cell culture after isolation from the fresh tissues. We do not have to worry given Peprotech's quality. Even during this pandemic, the supply did not interrupt. That helped us to keep our research going! Keep it up!

Von: Munjal | Datum: 28.08.2020

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