Recombinant Murine MIP-3β (CCL19)

Produktdetails

Katalognummer: 250-27B

Beschreibung:

MIP-3β is a CC chemokine, expressed in the thymus, lymph nodes, and in activated bone marrow stromal cells that signals through the CCR7 receptor. MIP-3β is a chemoattractant for T and B lymphocytes, and myeloid progenitor cells. Human MIP-3β is active on murine cells. Recombinant Murine MIP-3β is a 9.2 kDa protein containing 83 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

Source: E.coli

Synonyms: Macrophage Inflammatory Protein-3β, CCL19, ELC, Exodus-3, SCYA19

AA Sequence: GANDAEDCCL SVTQRPIPGN IVKAFRYLLN EDGCRVPAVV FTTLRGYQLC APPDQPWVDR IIRRLKKSSA KNKGNSTRRS PVS

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract activated human T cells expressing the CCR7 receptor. The ED₅₀ for this effect is 30-90 ng/ml.

Calculated Molecular Weight: 9.2 kDa

Accession Number: O70460

Gene ID: 24047

Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)

crossreactivity:

Human, Human + Mouse, Monkey, Mouse, Rat

Country Of Origin: USA

Not for human use.

Research Interest

Chemotaxis

Immune System

Wound Healing

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Erstautor

Tse, B C

Titel

Exposure to Systemic Immunosuppressive Ultraviolet Radiation Alters T Cell Recirculation through Sphingosine-1-Phosphate.

Literaturstelle

Journal of immunology (Baltimore, Md. : 1950); 207(9) pg2278-2287

PubMed ID

34561229

Erstautor

Qin, T

Titel

Mucosal Vaccination for Influenza Protection Enhanced by Catalytic Immune-Adjuvant.

Literaturstelle

Advanced science (Weinheim, Baden-Wurttemberg, Germany); 7(18) pg2000771

PubMed ID

32999833

Erstautor

Cain, D W

Titel

Murine Glucocorticoid Receptors Orchestrate B Cell Migration Selectively between Bone Marrow and Blood.

Literaturstelle

Journal of immunology (Baltimore, Md. : 1950); 205(3) pg619-629

PubMed ID

32571841

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migration assays

works well for dendritic cells in migration assays!

Von: Caitlin | Datum: 13.07.2020

Chemokine