Recombinant Human LEC (CCL16) 0 AvisSubmit a Review Détails du Produit Catalog Number: 300-44 Description: LEC is a CC chemokine that can signal through the CCR8 and CCR1 receptors. It is expressed in the liver, spleen, and thymus. LEC is chemotactic towards monocytes and lymphocytes, but not neutrophils. Recombinant Human LEC is an 11.2 kDa protein containing 97 amino acid residues, including the four conserved cysteine residues present in CC chemokines. Source: E.coli Synonyms: Liver-Expressed Chemokine, CCL16, NCC-4, HCC-4, LMC, LCC-1, MTN-1, IL-10-inducible chemokine AA Sequence: QPKVPEWVNT PSTCCLKYYE KVLPRRLVVG YRKALNCHLP AIIFVTKRNR EVCTNPNDDW VQEYIKDPNL PLLPTRNLST VKIITAKNGQ PQLLNSQ Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract total human monocytes using a concentration range of 10-100 ng/ml. Calculated Molecular Weight: 11.2 kDa Accession Number: O15467 Gene ID: 6360 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Bacteria, Human, Mouse References PubMed SDS Recherche de CoA Product Line Country Of Origin: USA Not for human use. Research Interest Chemotaxis Immune System Wound Healing product.subtitle.recentcitations Premier Auteur Lee, A W Titre A knottin scaffold directs the CXC-chemokine-binding specificity of tick evasins. Citation The Journal of Biological Chemistry; 294(29) pg11199-11212 Id PubMed 31167786 Premier Auteur Alenazi, Y Titre Genetically engineered two-warhead evasins provide a method to achieve precision targeting of disease-relevant chemokine subsets. Citation Scientific Reports; 8(1) pg6333 Id PubMed 29679010 Premier Auteur Yagawa, Y Titre Systematic Screening of Chemokines to Identify Candidates to Model and Create Ectopic Lymph Node Structures for Cancer Immunotherapy. Citation Scientific Reports; 7(1) pg15996 Id PubMed 29167448