Recombinant Murine Eotaxin (CCL11) 0 AvisSubmit a Review Détails du Produit Catalog Number: 250-01 Description: Eotaxin is a CC chemokine that signals through the CCR3 receptor. It is produced by IFN-γ-stimulated endothelial cells and TNF-activated monocytes. Eotaxin selectively chemoattracts eosinophils and, along with Eotaxin-2 and Eotaxin-3, plays a key role in the regulation of eosinophil recruitment in the asthmatic lung and in allergic reactions. Recombinant Murine Eotaxin is an 8.4 kDa protein containing 74 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. Source: E.coli Synonyms: CCL11 AA Sequence: HPGSIPTSCC FIMTSKKIPN TLLKSYKRIT NNRCTLKAIV FKTRLGKEIC ADPKKKWVQD ATKHLDQKLQ TPKP Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Murine Eotaxin was found to induce chemotaxis of purified eosinophils at concentrations ranging between 10-100 ng/ml. Calculated Molecular Weight: 8.4 kDa Accession Number: P48298 Gene ID: 20292 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Human, Mouse, Rat References PubMed SDS Recherche de CoA Product Line Country Of Origin: USA Not for human use. Research Interest Chemotaxis Immune System Neurobiology Wound Healing product.subtitle.recentcitations Premier Auteur Felton, J M Titre Aiolos regulates eosinophil migration into tissues Citation Mucosal Immunology; 14(6) pg1271-1281 Id PubMed 34341502 Premier Auteur Patial, S Titre Myeloid-IL4Rα is an indispensable link in IL-33-ILCs-IL-13-IL4Rα axis of eosinophil recruitment in murine lungs. Citation Scientific Reports; 11(1) pg15465 Id PubMed 34326406 Premier Auteur Dileepan, M Titre Regulation of Eosinophil Recruitment and Allergic Airway Inflammation by Tropomyosin Receptor Kinase A. Citation Journal of Immunology; 204(3) pg682-693 Id PubMed 31871023
