Recombinant Murine LIX (CXCL6) (70 a.a.) 0 AvisSubmit a Review Détails du Produit Catalog Number: 250-36 Description: CXCL6, also known as LIX in mice, is a CXC chemokine that signals through the CXCR2 receptor. It is expressed in monocytes, platelets, endothelial cells, and mast cells. LIX is a chemoattractant for neutrophils. The two naturally occurring variants of LIX, LIX 1-78 (GCP-2) and LIX 9-78 (GCP-2), contain 78 and 70 amino acid residues, respectively. LIX contains the four conserved cysteine residues present in CXC chemokines, and also contains the ‘ELR’ motif common to CXC chemokines that binds to the CXCR1 and CXCR2 receptors. Recombinant Murine LIX is a 7.6 kDa protein consisting of amino acid residues 9-78 of the full length LIX protein (70 amino acids). Source: E.coli AA Sequence: TELRCVCLTV TPKINPKLIA NLEVIPAGPQ CPTVEVIAKL KNQKEVCLDP EAPVIKKIIQ KILGSDKKKA Synonyms: CXCL6, GCP-2 (human), Granulocyte Chemotactic Protein-2 Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Not available. Calculated Molecular Weight: 7.6 kDa Accession Number: P50228 Gene ID: 20311 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Human, Mouse References PubMed SDS Recherche de CoA Product Line Country Of Origin: USA Not for human use. Research Interest Angiogenesis/Cardiovascular Bone, Skeletal, Cartilage Chemotaxis Immune System Inflammation Wound Healing product.subtitle.recentcitations Premier Auteur Singh, K Titre Yeast surface display identifies a family of evasins from ticks with novel polyvalent CC chemokine-binding activities. Citation Scientific Reports; 7(1) pg4267 Id PubMed 28655871 Premier Auteur Rousselle, A Titre CXCL5 limits macrophage foam cell formation in atherosclerosis. Citation The Journal of Clinical Investigation; 123(3) pg1343-7 Id PubMed 23376791 Premier Auteur Mei, J Titre CXCL5 regulates chemokine scavenging and pulmonary host defense to bacterial infection. Citation Immunity; 33(1) pg106-17 Id PubMed 20643340
