Recombinant Murine MIG (CXCL9) 0 AvisSubmit a Review Détails du Produit Catalog Number: 250-18 Description: MIG, a CXC chemokine, is produced by IFN-γ stimulated monocytes, macrophages and endothelial cells. It signals through the CXCR3 receptor. MIG selectively chemoattracts Th1 lymphocytes, and also exerts other activities, including inhibition of tumor growth, angiogenesis, and inhibition of colony formation of hematopoietic progenitors. Human MIG is active on murine cells. Recombinant Murine MIG is a 12.2 kDa protein containing 105 amino acid residues, including the four highly conserved cysteine residues present in CXC chemokines. Source: E.coli Synonyms: Monokine Induced by Interferon-gamma, CXCL9 AA Sequence: TLVIRNARCS CISTSRGTIH YKSLKDLKQF APSPNCNKTE IIATLKNGDQ TCLDPDSANV KKLMKEWEKK INQKKKQKRG KKHQKNMKNR KPKTPQSRRR SRKTT Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human activated T cells cultured in the presence of IL-2 using a concentration range of 50.0-150.0 ng/ml. Calculated Molecular Weight: 12.2 kDa Accession Number: P18340 Gene ID: 17329 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Bacteria, Human, Monkey, Mouse, References PubMed SDS Recherche de CoA Product Line Country Of Origin: USA Not for human use. Research Interest COVID-19 Angiogenesis/Cardiovascular Chemotaxis Immune System Inflammation Wound Healing Transplantation product.subtitle.recentcitations Premier Auteur Pein, M Titre Metastasis-initiating cells induce and exploit a fibroblast niche to fuel malignant colonization of the lungs Citation Nature Communications; 11(1) pg1494 Id PubMed 32198421 Premier Auteur Joutoku, Z Titre CCL21/CCR7 axis regulating juvenile cartilage repair can enhance cartilage healing in adults. Citation Stem Cell Reports; 9(1) pg5165 Id PubMed 30914733 Premier Auteur Xu, Y Titre Sipa1 deficiency unleashes a host-immune mechanism eradicating chronic myelogenous leukemia-initiating cells. Citation Nature Communications; 9(1) pg914 Id PubMed 29500416
