PeproGMP® Recombinant Human Flt3-Ligand 0 评论Submit a Review 产品详情 产品编号： GMP300-19 产品描述： Flt3-Ligand is a growth factor that regulates proliferation of early hematopoietic cells. Flt3-Ligand binds to cells expressing the tyrosine kinase receptor Flt3. Flt3-Ligand, by itself does not stimulate proliferation of early hematopoietic cells, but synergizes with other CSFs and interleukins to induce growth and differentiation. Unlike SCF, Flt3-Ligand exerts no activity on mast cells. Multiple isoforms of Flt3-Ligand have been identified. The predominant biologically active form is anchored to the cell surface as the extracellular domain of a transmembrane protein (209 a.a.). The membrane-bound isoform can be proteolytically cleaved to generate a biologically active soluble isoform. •Additional product information and specifications are provided on the Certificate of Analysis. Note: All of PeproTech's GMP products are manufactured using animal-derived component free materials. Source: E.coli Synonyms: Fms-related tyrosine kinase 3 ligand, Flt3L AA Sequence: MTQDCSFQHSP ISSDFAVKIR ELSDYLLQDY PVTVASNLQD EELCGGLWRL VLAQRWMERL KTVAGSKMQG LLERVNTEIH FVTKCAFQPP PSCLRFVQTN ISRLLQETSE QLVALKPWIT RQNFSRCLEL QCQPDSSTLP PPWSPRPLEA TAPTA Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Accession Number: P49771 Gene ID: 2322 PubMed CoA 搜索 Product Line Country Of Origin: USA Not for human use. Research Interest 癌症 细胞培养 免疫系统 增殖 干细胞&分化
