Recombinant Human BCMA 0 评论Submit a Review 产品详情 产品编号: 310-16 产品描述: BCMA, a member of the TNF receptor superfamily, binds to BAFF and APRIL. BCMA is expressed on mature B cells and other B cell lines, and plays an important role in B cell development, function and regulation. BCMA also has the capability to activate NF-κB and JNK. The human BCMA gene codes for a 184 amino acid type I transmembrane protein, which contains a 54 amino acid extracellular domain, a 23 amino acid transmembrane domain, and a 107 amino acid cytoplasmic domain. Recombinant soluble Human BCMA is a 50 amino acid polypeptide (5.3 kDa) comprising the TNFR homologous region of the BCMA protein. Source: E.coli Synonyms: B-Cell Maturation Antigen, TNFRSF17, BCM AA Sequence: AGQCSQNEYF DSLLHACIPC QLRCSSNTPP LTCQRYCNAS VTNSVKGTNA Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Not available. Calculated Molecular Weight: 5.3 kDa Accession Number: Q02223 Gene ID: 608 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Human References PubMed SDS CoA 搜索 Product Line Country Of Origin: USA Not for human use. Research Interest 细胞凋亡 免疫系统 炎症 TNF超家族 product.subtitle.recentcitations 第一作者 Pont, M 标题 γ-Secretase inhibition increases efficacy of BCMA-specific chimeric antigen receptor T cells in multiple myeloma. 文献引用 Blood; 134(19) pg1585-1597 PubMed Id 31558469