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趋化因子

Recombinant Human CTACK (CCL27)

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产品详情

产品编号: 300-54
产品描述:
Recombinant Human CTACK (CCL27)

CTACK is a keratinocyte-derived CC chemokine which signals through the CCR10 receptor. Both CTACK and CCR10 are expressed in normal and irritated epithelial cells. CTACK selectively attracts CLA+ T cells and directs them into the skin. CTACK contains the four highly conserved cysteine residues present in most CC chemokines. The mature protein contains 88 amino acid residues. Recombinant Human CTACK is a 10.2 kDa protein containing 88 amino acid residues.

Source: E.coli

Synonyms: Cutaneous T-cell Attracting Chemokine, CCL27, ALP, Skinkine, Eskine

AA Sequence: FLLPPSTACC TQLYRKPLSD KLLRKVIQVE LQEADGDCHL QAFVLHLAQR SICIHPQNPS LSQWFEHQER KLHGTLPKLN FGMLRKMG

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract CXCR3 transfected cells using a concentration of 10.0-100.0 ng/ml.

Recombinant Human CTACK (CCL27) Biological Activity Graph

Calculated Molecular Weight: 10.2 kDa

Accession Number: Q9Y4X3

Gene ID: 10850

Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

第一作者
Lee, A W
标题
A knottin scaffold directs the CXC-chemokine-binding specificity of tick evasins.
文献引用
The Journal of Biological Chemistry; 294(29) pg11199-11212
PubMed Id
第一作者
Alenazi, Y
标题
Genetically engineered two-warhead evasins provide a method to achieve precision targeting of disease-relevant chemokine subsets.
文献引用
Scientific Reports; 8(1) pg6333
PubMed Id
第一作者
Buskermolen, J K
标题
Stimulation of oral fibroblast chemokine receptors identifies CCR3 and CCR4 as potential wound healing targets.
文献引用
Journal of Cellular Physiology; 232(11) pg2996-3005
PubMed Id