Recombinant Human FGF-6 0 评论Submit a Review 产品详情 产品编号： 100-30 产品描述： FGF-6 is a secreted, heparin-binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-6 is expressed in leukemia cell lines with platelet megakaryocytic differentiation potential. It signals through FGFR 1c, 2c, and 4. Recombinant Human FGF-6 is an 18.7 kDa protein consisting of 168 amino acid residues. Source: E.coli Synonyms: Fibroblast Growth Factor-6, HBGF-6, HST-2 AA Sequence: GTRANNTLLD SRGWGTLLSR SRAGLAGEIA GVNWESGYLV GIKRQRRLYC NVGIGFHLQV LPDGRISGTH EENPYSLLEI STVERGVVSL FGVRSALFVA MNSKGRLYAT PSFQEECKFR ETLLPNNYNA YESDLYQGTY IALSKYGRVK RGSKVSPIMT VTHFLPRI Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors. The expected ED50 is ≤ 0.5 ng/ml corresponding to a specific activity of ≥ 2 x 106 units/mg. Calculated Molecular Weight: 18.7 kDa Accession Number: P10767 Gene ID: 2251 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Human, Mouse, References PubMed SDS CoA 搜索 Product Line Country Of Origin: USA Not for human use. Research Interest 血管生成/心血管 骨/骨骼系统/软骨 癌症 FGF超家族 免疫系统 炎症 神经生物学 干细胞&分化 创伤修复 product.subtitle.recentcitations 第一作者 Savchenko, E 标题 FGF family members differentially regulate maturation and proliferation of stem cell-derived astrocytes. 文献引用 Scientific Reports; 9(1) pg9610 PubMed Id 31270389 第一作者 Ishihara, J 标题 Laminin heparin-binding peptides bind to several growth factors and enhance diabetic wound healing. 文献引用 Nature Communications; 9(1) pg2163 PubMed Id 29867149 第一作者 Shee, K 标题 Therapeutically targeting tumor microenvironment-mediated drug resistance in estrogen receptor-positive breast cancer. 文献引用 The Journal of Experimental Medicine; 215(3) pg895-910 PubMed Id 29436393
