Animal-Free Recombinant Human FGF-basic (154 a.a.) 1 评论Submit a Review 产品详情 产品编号： AF-100-18B 产品描述： FGF-basic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-basic is a non-glycosylated, heparin-binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland, liver, monocytes, epithelial cells and endothelial cells. FGF-basic signals through FGFR 1b, 1c, 2c, 3c and 4. Recombinant Human FGF-basic is a 17.2 kDa protein consisting of 154 amino acid residues. Qualified for stem cell use. Manufactured using all Animal-Free reagents. Source: E.coli Synonyms: Fibroblast Growth Factor-basic, FGF-2, HBGF-2, Prostatropin AA Sequence: AAGSITTLPA LPEDGGSGAF PPGHFKDPKR LYCKNGGFFL RIHPDGRVDG VREKSDPHIK LQLQAEERGV VSIKGVCANR YLAMKEDGRL LASKCVTDEC FFFERLESNN YNTYRSRKYT SWYVALKRTG QYKLGSKTGP GQKAILFLPM SAKS Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by a cell proliferation assay using Balb/c 3T3 cells. The expected ED50 is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg. This product has been tested against the WHO standard. International Unit information can be found here. Calculated Molecular Weight: 17.2 kDa Accession Number: P09038 Gene ID: 2247 Endotoxin: Endotoxin level is < 0.01 ng/ug of protein (< 0.1 EU/ug) crossreactivity: Chicken, Cow, Dog, Frog, Hamster, Horse, Human, Human + Hamster, Human + Mouse, Human + Virus, Monkey, Mouse, Pig, Rabbit, Rat, Rat + Chicken, Salamander, Sheep, Zebra Fish References PubMed SDS CoA 搜索 Product Line Country Of Origin: USA Not for human use. Research Interest Organoids 血管生成/心血管 骨/骨骼系统/软骨 癌症 细胞培养 FGF超家族 免疫系统 炎症 神经生物学 干细胞&分化 创伤修复 糖尿病/体重调节 product.subtitle.recentcitations 第一作者 Zhang, X 标题 FOXF2 oppositely regulates stemness in luminal and basal-like breast cancer cells through the Wnt/beta-catenin pathway. 文献引用 The Journal of Biological Chemistry; 298(7) pg102082 PubMed Id 35660418 第一作者 Liu, Y 标题 Paradoxical role of β8 integrin on angiogenesis and vasculogenic mimicry in glioblastoma. 文献引用 Cell death & disease; 13(6) pg536 PubMed Id 35676251 第一作者 Laucirica, D R 标题 Pseudomonas aeruginosa modulates neutrophil granule exocytosis in an in vitro model of airway infection. 文献引用 Immunology and Cell Biology; 100(5) pg352-370 PubMed Id 35318736 product.subtitle.productreviews 现有评论 Worked well for research purposes We used this product in one of our orthopedic research studies. Product arrived quickly and was packaged well. Would purchase again. 来自: Emilie | 日期: 2020/8/26 × Worked well for research purposes We used this product in one of our orthopedic research studies. Product arrived quickly and was packaged well. Would purchase again. 来自: Emilie | 日期: 2020/8/26 Close
