Animal-Free Recombinant Human G-CSF 0 评论Submit a Review 产品详情 产品编号: AF-300-23 产品描述: G-CSF is a hematopoietic growth factor that stimulates the development of committed progenitor cells to neutrophils and enhances the functional activities of the mature end-cell. It is produced in response to specific stimulation by a variety of cells, including macrophages, fibroblasts, endothelial cells and bone marrow stroma. G-CSF is being used clinically to facilitate hematopoietic recovery after bone marrow transplantation. Human and murine G-CSF are cross-species reactive. Recombinant Human G-CSF is an 18.7 kDa protein consisting of 174 amino acid residues. Manufactured using all Animal-Free reagents. Source: E.coli Synonyms: Granulocyte Colony-Stimulating Factor, CSF-3, MGI-1G, GM-CSFβ, pluripoietin AA Sequence: TPLGPASSLP QSFLLKCLEQ VRKIQGDGAA LQEKLCATYK LCHPEELVLL GHSLGIPWAP LSSCPSQALQ LAGCLSQLHS GLFLYQGLLQ ALEGISPELG PTLDTLQLDV ADFATTIWQQ MEELGMAPAL QPTQGAMPAF ASAFQRRAGG VLVASHLQSF LEVSYRVLRH LAQP Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to stimulate the proliferation of mouse NFS-60 cells. The expected ED50 is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg. This product has been tested against the WHO standard. International Unit information can be found here. Calculated Molecular Weight: 18.7 kDa Accession Number: P09919 Gene ID: 1440 Endotoxin: Endotoxin level is < 0.01 ng/ug of protein (< 0.1 EU/ug) crossreactivity: Human, Mouse, Plant References PubMed SDS CoA 搜索 Product Line Country Of Origin: USA Not for human use. Research Interest 艾滋病/HIV 血管生成/心血管 癌症 糖尿病/体重调节 免疫系统 炎症 干细胞&分化 product.subtitle.recentcitations 第一作者 Murthy, S 标题 Danger signal extracellular calcium initiates differentiation of monocytes into SPP1/osteopontin-producing macrophages. 文献引用 Cell death & disease; 13(1) pg53 PubMed Id 35022393 第一作者 Thomé, C H 标题 NTAL is associated with treatment outcome, cell proliferation and differentiation in acute promyelocytic leukemia 文献引用 Scientific Reports; 10(1) pg10315 PubMed Id 32587277 第一作者 Xu, Y 标题 TAF1 plays a critical role in AML1-ETO driven leukemogenesis. 文献引用 Nature Communications; 10(1) pg4925 PubMed Id 31664040