Recombinant Human IL-3 1 评论Submit a Review 产品详情 产品编号： 200-03 产品描述： IL-3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoiesis, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles. Many of the IL-3 activities depend upon co-stimulation with other cytokines. IL-3 is a species-specific, variably glycosylated cytokine. Recombinant Human IL-3 is a 15.0 kDa globular protein containing 133 amino acid residues. Source: E.coli Synonyms: Interleukin-3, MCGF (Mast cell growth factor), Multi-CSF, HCGF, P-cell stimulation factor AA Sequence: APMTQTTSLK TSWVNCSNMI DEIITHLKQP PLPLLDFNNL NGEDQDILME NNLRRPNLEA FNRAVKSLQN ASAIESILKN LLPCLPLATA APTRHPIHIK DGDWNEFRRK LTFYLKTLEN AQAQQTTLSL AIF Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: The ED50 as determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg. This product has been tested against the WHO standard. International Unit information can be found here. Calculated Molecular Weight: 15 kDa Accession Number: P08700 Gene ID: 3562 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Bacteria, Human, Human + Hamster, Human + Mouse, Human + Virus, Leech, Monkey, Mouse References PubMed SDS CoA 搜索 Product Line Country Of Origin: USA Not for human use. Research Interest 艾滋病/HIV 癌症 糖尿病/体重调节 免疫系统 干细胞&分化 product.subtitle.recentcitations 第一作者 Thomas, G E 标题 The metabolic enzyme hexokinase 2 localizes to the nucleus in AML and normal haematopoietic stem and progenitor cells to maintain stemness. 文献引用 Nature Cell Biology; 24(6) pg872-884 PubMed Id 35668135 第一作者 Ackermann, M 标题 Continuous human iPSC-macrophage mass production by suspension culture in stirred tank bioreactors. 文献引用 Nature Protocols; 17(2) pg513-539 PubMed Id 35039668 第一作者 Wang, Y 标题 Using Cryo-ET to distinguish platelets during pre-acute myeloid leukemia from steady state hematopoiesis. 文献引用 Communications Biology; 5(1) pg72 PubMed Id 35058565 product.subtitle.productreviews 现有评论 IL3 for iPSC differentiation Much cheaper than other options present in the market and extremely efficient. I'd highly recommend it as it is easy to reconstitute and very dependable. 来自: Meenakshi | 日期: 2020/7/9 × IL3 for iPSC differentiation Much cheaper than other options present in the market and extremely efficient. I'd highly recommend it as it is easy to reconstitute and very dependable. 来自: Meenakshi | 日期: 2020/7/9 Close
