Recombinant Human NT-4 0 评论Submit a Review 产品详情 产品编号： 450-04 产品描述： NT-4 is a neurotrophic factor structurally related to β-NGF, BDNF, and NT-3. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-4 is expressed in the prostate, thymus, placenta, and skeletal muscle. NT-4 can signal through the LNGFR and trkB receptors, and promotes the survival of peripheral sensory sympathetic neurons. Recombinant Human NT-4 is a noncovalently linked homodimer of two 14.0 kDa polypeptide monomers (260 total amino acid residues). Source: E.coli Synonyms: Neurotrophin-4, Neurotrophic 4/5 (NT-4/NT-5) AA Sequence (monomer): GVSETAPASR RGELAVCDAV SGWVTDRRTA VDLRGREVEV LGEVPAAGGS PLRQYFFETR CKADNAEEGG PGAGGGGCRG VDRRHWVSEC KAKQSYVRAL TADAQGRVGW RWIRIDTACV CTLLSRTGRA Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to bind recombinant human TrkB Fc Chimera in a functional ELISA. Calculated Molecular Weight: 28.1 kDa Accession Number: P34130 Gene ID: 4909 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Frog, Human, Mouse, Rat References PubMed SDS CoA 搜索 Product Line Country Of Origin: USA Not for human use. Research Interest 糖尿病/体重调节 神经生物学 干细胞&分化 product.subtitle.recentcitations 第一作者 Zhu, Y 标题 Deep learning-based predictive identification of neural stem cell differentiation 文献引用 Nature Communications; 12(1) pg2614 PubMed Id 33972525 第一作者 Sun, X 标题 Functionally Distinct Neuronal Ensembles within the Memory Engram. 文献引用 Cell; 181(2) pg410-423.e17 PubMed Id 32187527 第一作者 Vandewauw, I 标题 A TRP channel trio mediates acute noxious heat sensing. 文献引用 Nature; 555(7698) pg662-666 PubMed Id 29539642
