Recombinant Human VEGF121 1 评论Submit a Review 产品详情 产品编号： 100-20A 产品描述： VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. VEGF signals through three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Due to its increased acidity, VEGF121 circulates more freely than other VEGF forms, which bind more tightly with vascular heparin sulfates. Recombinant Human VEGF121 is a 28.4 kDa, disulfide-linked homodimeric protein consisting of two 121 amino acid polypeptide chains. Source: E.coli Synonyms: Vascular Endothelial Growth Factor 121, VPF, VEGF-A AA Sequence (monomer): APMAEGGGQN HHEVVKFMDV YQRSYCHPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCGGC CNDEGLECVP TEESNITMQI MRIKPHQGQH IGEMSFLQHN KCECRPKKDR ARQENCDKPR R Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by the dose-dependent stimulation of the proliferation of human umbilical vein endothelial cells (HUVEC) using a concentration range of 0.2-0.4 ng/ml. Calculated Molecular Weight: 28.4 kDa Accession Number: P15692 Gene ID: 7422 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Chicken, Dog, Human, Mouse, Rabbit, Rat, Sheep References PubMed SDS CoA 搜索 Product Line Country Of Origin: USA Not for human use. Research Interest 血管生成/心血管 癌症 免疫系统 炎症 神经生物学 干细胞&分化 product.subtitle.recentcitations 第一作者 Hu, L 标题 Endothelial cell-derived Apelin inhibits tumor growth by altering immune cell localization 文献引用 Scientific Reports; 11(1) pg14047 PubMed Id 34234274 第一作者 Cohen, S 标题 Generation of vascular chimerism within donor organs 文献引用 Scientific Reports; 11(1) pg13437 PubMed Id 34183759 第一作者 Seki, T 标题 Interleukin-6 as an enhancer of anti-angiogenic therapy for ovarian clear cell carcinoma 文献引用 Scientific Reports; 11(1) pg7689 PubMed Id 33833265 product.subtitle.productreviews 现有评论 high quality product for vascular biology research We use this product in our project for more than 5 years, by which the hiPSC-derived vascular endothelial cell were differentiated 来自: Ping | 日期: 2020/8/26 × high quality product for vascular biology research We use this product in our project for more than 5 years, by which the hiPSC-derived vascular endothelial cell were differentiated 来自: Ping | 日期: 2020/8/26 Close
