Animal-Free Recombinant Human VEGF121 0 评论Submit a Review 产品详情 产品编号： AF-100-20A 产品描述： VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. VEGF signals through three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Due to its increased acidity, VEGF121 circulates more freely than other VEGF forms, which bind more tightly with vascular heparin sulfates. Recombinant Human VEGF121 is a 28.4 kDa, disulfide-linked homodimeric protein consisting of two 121 amino acid polypeptide chains. Manufactured using all Animal-Free reagents. Source: E.coli Synonyms: Vascular Endothelial Growth Factor 121, VPF, VEGF-A AA Sequence (monomer): APMAEGGGQN HHEVVKFMDV YQRSYCHPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCGGC CNDEGLECVP TEESNITMQI MRIKPHQGQH IGEMSFLQHN KCECRPKKDR ARQENCDKPR R Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Calculated Molecular Weight: 28.4 kDa Biological Activity: Determined by the dose-dependent stimulation of the proliferation of human umbilical vein endothelial cells (HUVEC) using a concentration range of 0.2-0.4 ng/ml. Accession Number: P15692 Gene ID: 7422 Endotoxin: Endotoxin level is < 0.01 ng/ug of protein (< 0.1 EU/ug) crossreactivity: Chicken, Human, Mouse, Rabbit, Sheep References PubMed SDS CoA 搜索 Product Line Country Of Origin: USA Not for human use. Research Interest 血管生成/心血管 癌症 免疫系统 炎症 神经生物学 干细胞&分化 product.subtitle.recentcitations 第一作者 Szczepkowska, A 标题 Pattern of expression of vascular endothelial growth factor and its receptors in the ovine choroid plexus during long and short photoperiods. 文献引用 Cell and Tissue Research; 350(1) pg157-66 PubMed Id 22622803 第一作者 Ferro, F 标题 Dental pulp stem cells differentiation reveals new insights in Oct4A dynamics. 文献引用 PLoS ONE; 7(7) pge41774 PubMed Id 22844522 第一作者 Sachdeva, R 标题 Transgenesis-mediated reproductive dysfunction and tumorigenesis: effects of immunological neutralization. 文献引用 PLoS ONE; 7(11) pge51125 PubMed Id 23226476
