Recombinant Murine Eotaxin (CCL11) 0 评论Submit a Review 产品详情 产品编号： 250-01 产品描述： Eotaxin is a CC chemokine that signals through the CCR3 receptor. It is produced by IFN-γ-stimulated endothelial cells and TNF-activated monocytes. Eotaxin selectively chemoattracts eosinophils and, along with Eotaxin-2 and Eotaxin-3, plays a key role in the regulation of eosinophil recruitment in the asthmatic lung and in allergic reactions. Recombinant Murine Eotaxin is an 8.4 kDa protein containing 74 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. Source: E.coli Synonyms: CCL11 AA Sequence: HPGSIPTSCC FIMTSKKIPN TLLKSYKRIT NNRCTLKAIV FKTRLGKEIC ADPKKKWVQD ATKHLDQKLQ TPKP Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Murine Eotaxin was found to induce chemotaxis of purified eosinophils at concentrations ranging between 10-100 ng/ml. Calculated Molecular Weight: 8.4 kDa Accession Number: P48298 Gene ID: 20292 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Human, Mouse, Rat References PubMed SDS CoA 搜索 Product Line Country Of Origin: USA Not for human use. Research Interest 化学趋化 免疫系统 神经生物学 创伤修复 product.subtitle.recentcitations 第一作者 Felton, J M 标题 Aiolos regulates eosinophil migration into tissues 文献引用 Mucosal Immunology; 14(6) pg1271-1281 PubMed Id 34341502 第一作者 Patial, S 标题 Myeloid-IL4Rα is an indispensable link in IL-33-ILCs-IL-13-IL4Rα axis of eosinophil recruitment in murine lungs. 文献引用 Scientific Reports; 11(1) pg15465 PubMed Id 34326406 第一作者 Dileepan, M 标题 Regulation of Eosinophil Recruitment and Allergic Airway Inflammation by Tropomyosin Receptor Kinase A. 文献引用 Journal of Immunology; 204(3) pg682-693 PubMed Id 31871023
