Recombinant Murine G-CSF 0 评论Submit a Review 产品详情 产品编号: 250-05 产品描述: G-CSF is a hematopoietic growth factor that stimulates the development of committed progenitor cells to neutrophils and enhances the functional activities of the mature end-cell. It is produced in response to specific stimulation by a variety of cells, including macrophages, fibroblasts, endothelial cells and bone marrow stroma. G-CSF is being used clinically to facilitate hematopoietic recovery after bone marrow transplantation. Human and murine G-CSF are cross-species reactive. Recombinant Murine G-CSF is a 19.0 kDa protein consisting of 179 amino acid residues. Source: E.coli Synonyms: Granulocyte Colony-Stimulating Factor, CSF-3, MGI-1G, GM-CSFb, pluripoietin AA Sequence: MVPLVTVSAL PPSLPLPRSF LLKSLEQVRK IQASGSVLLE QLCATYKLCH PEELVLLGHS LGIPKASLSG CSSQALQQTQ CLSQLHSGLC LYQGLLQALS GISPALAPTL DLLQLDVANF ATTIWQQMEN LGVAPTVQPT QSAMPAFTSA FQRRAGGVLA ISYLQGFLET ARLALHHLA Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: The ED50 was determined by the dose-dependent stimulation of the proliferation of murine NFS-60 cells is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 107 units/mg. Calculated Molecular Weight: 19 kDa Accession Number: P09920 Gene ID: 12985 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Human, Monkey, Mouse, Rat References PubMed SDS CoA 搜索 Product Line Country Of Origin: USA Not for human use. Research Interest 艾滋病/HIV 血管生成/心血管 癌症 糖尿病/体重调节 免疫系统 炎症 干细胞&分化 product.subtitle.recentcitations 第一作者 Dai, Y 标题 Meteorin links the bone marrow hypoxic state to hematopoietic stem/progenitor cell mobilization. 文献引用 Cell Reports; 40(12) pg111361 PubMed Id 36130501 第一作者 Tritz, R 标题 MEK inhibition exerts temporal and myeloid cell-specific effects in the pathogenesis of neurofibromatosis type 1 arteriopathy. 文献引用 Scientific Reports; 11(1) pg24345 PubMed Id 34934133 第一作者 Stamos, D B 标题 The histone demethylase Lsd1 regulates multiple repressive gene programs during T cell development. 文献引用 The Journal of Experimental Medicine; 218(12) PubMed Id 34726730