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生长因子和细胞因子

Recombinant Murine IL-7

产品详情

产品编号: 217-17
产品描述:
Recombinant Murine IL-7

IL-7 is a hematopoietic growth factor that primarily affects early B and T cells.  Produced by thymic stromal cells, spleen cells and keratinocytes, IL-7 can also co-stimulate the proliferation of mature T cells in combination with other factors, such as ConA and IL-2.  Human and murine IL-7 are cross-species reactive.  Recombinant Murine IL-7 is a 15.0 kDa protein containing 130 amino acid residues.

Note:

This item is currently on indefinite backorder.

Synonyms: Lymphopoietin 1(LP-1), pre-B cell factor

Source: E.coli

AA Sequence: MECHIKDKEG KAYESVLMIS IDELDKMTGT DSNCPNNEPN FFRKHVCDDT KEAAFLNRAA RKLKQFLKMN ISEEFNVHLL TVSQGTQTLV NCTSKEEKNV KEQKKNDACF LKRLLREIKT CWNKILKGSI

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: The ED50 as determined by the dose-dependent stimulation of the proliferation of murine 2E8 cells is ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 106 units/mg.

Recombinant Murine IL-7 Biological Activity Graph

Calculated Molecular Weight: 15 kDa

Accession Number: P10168

Gene ID: 16196

Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

第一作者
Ashby, J F
标题
Microfluidic T Cell Selection by Cellular Avidity.
文献引用
Advanced Healthcare Materials; 11(16) pge2200169
PubMed Id
第一作者
Han, J
标题
Hypoxia induces adrenomedullin from lung epithelia, stimulating ILC2 inflammation and immunity.
文献引用
The Journal of Experimental Medicine; 219(6)
PubMed Id
第一作者
Nayak, R C
标题
Nuclear Vav3 is required for polycomb repression complex-1 activity in B-cell lymphoblastic leukemogenesis.
文献引用
Nature Communications; 13(1) pg3056
PubMed Id

product.subtitle.productreviews

现有评论
Works everytime
Happy to use this cytokine. Very efficient and economically priced. The product comes with all the relevant information and protocols on handling. Very helpful for expanding T cells and during ACT experiments.
来自:  Vineet | 日期:  2020/8/10
Great pro-survival cytokine for mouse T cells
We routinely use this great cytokine to generate mouse memory CD8+ T cells and also keep naive T cells alive. The pricing and consistency of this cytokine can't be beat.
来自:  Chirag | 日期:  2020/8/31