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生长因子和细胞因子

Recombinant Murine IL-9

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产品详情

产品编号: 219-19
产品描述:
Recombinant Murine IL-9


Recombinant Murine IL-9

IL-9 is an immunoregulatory cytokine produced by IL-2 activated Th2 lymphocytes.  IL-9 enhances the proliferation of T lymphocytes, mast cells, erythroid precursor cells and megakaryoblastic leukemia cell lines.  Over-expression of IL-9 has been implicated in the pathogenesis of anaplastic lymphoma and Hodgkin’s disease.  Whereas murine IL-9 can function on human cells, human IL-9 is inactive on mouse cells.  Recombinant Murine IL-9 is a 14.3 kDa protein of 127 amino acid residues, including 10 cysteine residues that are fully conserved between the human and murine proteins.

Source: E.coli

Synonyms: p40 cytokine, T-cell growth factor p40

AA Sequence: MQRCSTTWGI RDTNYLIENL KDDPPSKCSC SGNVTSCLCL SVPTDDCTTP CYREGLLQLT NATQKSRLLP VFHRVKRIVE VLKNITCPSF SCEKPCNQTM AGNTMSFLKS LLGTFQKTEM QRQKSRP

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: The ED50 as determined by the dose-dependent proliferation of human MO7e cells is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 units/mg.

Recombinant Murine IL-9 Biological Activity Graph

Calculated Molecular Weight: 14.3 kDa

Accession Number: P15247

Gene ID: 16198

Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

第一作者
Piseddu, I
标题
Constitutive Expression of CCL22 Is Mediated by T Cell-Derived GM-CSF.
文献引用
Journal of immunology (Baltimore, Md. : 1950); 205(8) pg2056-2065
PubMed Id
第一作者
Venturutti, L
标题
TBL1XR1 Mutations Drive Extranodal Lymphoma by Inducing a Pro-tumorigenic Memory Fate.
文献引用
Cell; 182(2) pg297-316.e27
PubMed Id
第一作者
Delacher, M
标题
Precursors for Nonlymphoid-Tissue Treg Cells Reside in Secondary Lymphoid Organs and Are Programmed by the Transcription Factor BATF.
文献引用
Immunity; 52(2) pg295-312.e11
PubMed Id