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趋化因子

Recombinant Murine KC (CXCL1)

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产品详情

产品编号: 250-11
产品描述:
Recombinant Murine KC (CXCL1)

All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant Murine KC is a 7.8 kDa protein consisting of 72 amino acids, including the 'ELR' motif common to the CXC chemokine family that binds to CXCR1 or CXCR2.

Source: E.coli

Synonyms: MGSAα, CXCL1, NAP-3, GRO1, GRO/MGSA (human), CINC (rat)

AA Sequence: APIANELRCQ CLQTMAGIHL KNIQSLKVLP SGPHCTQTEV IATLKNGREA CLDPEAPLVQ KIVQKMLKGV PK

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract total human neutrophil population using a concentration range of 10.0-100.0 ng/ml.

Recombinant Murine KC (CXCL1) Biological Activity Graph

Calculated Molecular Weight: 7.8 kDa

Accession Number: P12850

Gene ID: 14825

Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)

Note:

1mg will be provided as 2x500μg.

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

第一作者
Chang, C W
标题
13 Mediates Transendothelial Migration of Neutrophils by Promoting Integrin-Dependent Motility without Affecting Directionality.
文献引用
Journal of immunology (Baltimore, Md. : 1950); 207(12) pg3038-3049
PubMed Id
第一作者
Yoon, Y
标题
Activation of the adipocyte CREB/CRTC pathway in obesity.
文献引用
Communications Biology; 4(1) pg1214
PubMed Id
第一作者
Lindzen, M
标题
Targeting autocrine amphiregulin robustly and reproducibly inhibits ovarian cancer in a syngeneic model: roles for wildtype p53
文献引用
Oncogene; 40(21) pg3665-3679
PubMed Id