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趋化因子

Recombinant Murine MIG (CXCL9)

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产品详情

产品编号: 250-18
产品描述:
Recombinant Murine MIG (CXCL9)

MIG, a CXC chemokine, is produced by IFN-γ stimulated monocytes, macrophages and endothelial cells.  It signals through the CXCR3 receptor.  MIG selectively chemoattracts Th1 lymphocytes, and also exerts other activities, including inhibition of tumor growth, angiogenesis, and inhibition of colony formation of hematopoietic progenitors.  Human MIG is active on murine cells.  Recombinant Murine MIG is a 12.2 kDa protein containing 105 amino acid residues, including the four highly conserved cysteine residues present in CXC chemokines.

Source: E.coli

Synonyms: Monokine Induced by Interferon-gamma, CXCL9

AA Sequence: TLVIRNARCS CISTSRGTIH YKSLKDLKQF APSPNCNKTE IIATLKNGDQ TCLDPDSANV KKLMKEWEKK INQKKKQKRG KKHQKNMKNR KPKTPQSRRR SRKTT

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract human activated T cells cultured in the presence of IL-2 using a concentration range of 50.0-150.0 ng/ml.

Recombinant Murine MIG (CXCL9) Biological Activity Graph

Calculated Molecular Weight: 12.2 kDa

Accession Number: P18340

Gene ID: 17329

Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

第一作者
Pein, M
标题
Metastasis-initiating cells induce and exploit a fibroblast niche to fuel malignant colonization of the lungs
文献引用
Nature Communications; 11(1) pg1494
PubMed Id
第一作者
Joutoku, Z
标题
CCL21/CCR7 axis regulating juvenile cartilage repair can enhance cartilage healing in adults.
文献引用
Stem Cell Reports; 9(1) pg5165
PubMed Id
第一作者
Xu, Y
标题
Sipa1 deficiency unleashes a host-immune mechanism eradicating chronic myelogenous leukemia-initiating cells.
文献引用
Nature Communications; 9(1) pg914
PubMed Id