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Recombinant Murine MIP-2 (CXCL2)

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产品详情

产品编号: 250-15
产品描述:
Recombinant Murine MIP-2 (CXCL2)

All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant Murine MIP-2 is a 7.8 kDa protein consisting of 73 amino acids, including the 'ELR' motif common to the CXC chemokine family that binds to CXCR1 or CXCR2.

Source: E.coli

Synonyms: Macrophage Inflammatory Protein-2α, MIP-2α, Growth Regulated Protein/Melanoma Growth Stimulatory Activity (MGSAβ), CXCL2, GRO2

AA Sequence: AVVASELRCQ CLKTLPRVDF KNIQSLSVTP PGPHCAQTEV IATLKGGQKV CLDPEAPLVQ KIIQKILNKG KAN

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract total human neutrophils using a concentration range of 1.0-10.0 ng/ml.

Calculated Molecular Weight: 7.8 kDa

Accession Number: P10889

Gene ID: 20310

Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

第一作者
Yoon, Y
标题
Activation of the adipocyte CREB/CRTC pathway in obesity.
文献引用
Communications Biology; 4(1) pg1214
PubMed Id
第一作者
Chen, X
标题
Pinaverium Bromide Attenuates Lipopolysaccharide-Induced Excessive Systemic Inflammation via Inhibiting Neutrophil Priming.
文献引用
Journal of immunology (Baltimore, Md. : 1950); 206(8) pg1858-1865
PubMed Id
第一作者
Fonseca, K L
标题
Deficiency in the glycosyltransferase Gcnt1 increases susceptibility to tuberculosis through a mechanism involving neutrophils
文献引用
Mucosal Immunology; 13(5) pg836-848
PubMed Id