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趋化因子

Recombinant Murine PF-4 (CXCL4)

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产品详情

产品编号: 250-39
产品描述:
Recombinant Murine PF-4 (CXCL4)

PF-4 is a CXC chemokine that is expressed in megakaryocytes and stored in the α-granules of platelets. PF-4 is chemotactic towards neutrophils and monocytes, and has been shown to inhibit angiogenesis. Recombinant Murine PF-4 is an 8.2 kDa protein containing 76 amino acid residues, including the four highly conserved residues present in CXC chemokines.

Source: E.coli

Synonyms: Platelet Factor-4, CXCL4, Oncostatin A, Ironplact

AA Sequence: VTSAGPEESD GDLSCVCVKT ISSGIHLKHI TSLEVIKAGR HCAVPQLIAT LKNGRKICLD RQAPLYKKVI KKILES

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract human neutrophils using a concentration range of 10.0-100.0 ng/ml.

Calculated Molecular Weight: 8.2 kDa

Accession Number: Q9Z126

Gene ID: 56744

Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

第一作者
Du, Y
标题
Chemokines form nanoparticles with DNA and can superinduce TLR-driven immune inflammation.
文献引用
The Journal of Experimental Medicine; 219(7)
PubMed Id
第一作者
Yagawa, Y
标题
Systematic Screening of Chemokines to Identify Candidates to Model and Create Ectopic Lymph Node Structures for Cancer Immunotherapy.
文献引用
Scientific Reports; 7(1) pg15996
PubMed Id
第一作者
Singh, K
标题
Yeast surface display identifies a family of evasins from ticks with novel polyvalent CC chemokine-binding activities.
文献引用
Scientific Reports; 7(1) pg4267
PubMed Id