Recombinant Murine RANTES (CCL5) 0 评论Submit a Review 产品详情 产品编号： 250-07 产品描述： RANTES is a CC chemokine that can signal through the CCR1, CCR3, CCR5 and US28 (cytomegalovirus receptor) receptors. It is a chemoattractant towards monocytes, memory T cells (CD4+/CD45RO), basophils, and eosinophils. RANTES also has the capability to inhibit certain strains of HIV-1, HIV-2 and simian immunodeficiency virus (SIV). Recombinant Murine RANTES is a 7.8 kDa protein containing 68 amino acid residues, including the four highly conserved cysteine residues present in the CC chemokines. Source: E.coli Synonyms: Regulation upon Activation Normal T cell Express Sequence, CCL5, SIS-delta AA Sequence: SPYGSDTTPC CFAYLSLALP RAHVKEYFYT SSKCSNLAVV FVTRRNRQVC ANPEKKWVQE YINYLEMS Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human activated T cells cultured in the presence of IL-2 using a concentration range of 10-30 ng/ml. Calculated Molecular Weight: 7.8 kDa Accession Number: P30882 Gene ID: 20304 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Bacteria, Human, Leech, Mouse, Rat References PubMed SDS CoA 搜索 Product Line Country Of Origin: USA Not for human use. Research Interest 艾滋病/HIV 血管生成/心血管 化学趋化 免疫系统 炎症 神经生物学 创伤修复 过敏 移植 product.subtitle.recentcitations 第一作者 Du, Y 标题 Chemokines form nanoparticles with DNA and can superinduce TLR-driven immune inflammation. 文献引用 The Journal of Experimental Medicine; 219(7) PubMed Id 35640018 第一作者 Uzhachenko, R V 标题 Metabolic modulation by CDK4/6 inhibitor promotes chemokine-mediated recruitment of T cells into mammary tumors. 文献引用 Cell Reports; 35(1) pg108944 PubMed Id 33826903 第一作者 Lin, Y 标题 Neddylation pathway alleviates chronic pancreatitis by reducing HIF1α-CCL5-dependent macrophage infiltration. 文献引用 Cell death & disease; 12(3) pg273 PubMed Id 33723230
