Recombinant Murine SDF-1β (CXCL12) 0 评论Submit a Review 产品详情 产品编号： 250-20B 产品描述： SDF-1α and β are stromal-derived, CXC chemokines that signal through the CXCR4 receptor. SDF-1α and β chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 proteins exert HIV-suppressive activity in cells expressing the CXCR4 receptor. Human and murine SDF-1 proteins act across species. SDF-1α and β contain the four highly conserved cysteine residues present in CXC chemokines. The mature SDF-1β protein, produced by an N-terminal truncation of two additional amino acids, after removal of the signal sequence, contains 72 amino acid residues. Recombinant Murine SDF-1β is an 8.5 kDa protein containing 72 amino acid residues. Source: E.coli Synonyms: Stromal-Cell Derived Factor-1, CXCL12, PBSF AA Sequence: KPVSLSYRCP CRFFESHIAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNKRL KM Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human monocytes using a concentration range of 50.0-100.0 ng/ml. Calculated Molecular Weight: 8.5 kDa Accession Number: P40224 Gene ID: 20315 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Human, Mouse References PubMed SDS CoA 搜索 Product Line Country Of Origin: USA Not for human use. Research Interest 艾滋病/HIV 化学趋化 免疫系统 炎症 神经生物学 干细胞&分化 创伤修复 product.subtitle.recentcitations 第一作者 Lewis, R 标题 CXCR4 hyperactivation cooperates with TCL1 in CLL development and aggressiveness 文献引用 Leukemia; 35(10) pg2895-2905 PubMed Id 34363012 第一作者 Cruz-Zárate, D 标题 Myo1g is required for efficient adhesion and migration of activated B lymphocytes to inguinal lymph nodes 文献引用 Scientific Reports; 11(1) pg7197 PubMed Id 33785780 第一作者 Bénard, A 标题 Interleukin-3 is a predictive marker for severity and outcome during SARS-CoV-2 infections 文献引用 Nature Communications; 12(1) pg1112 PubMed Id 33602937
