Recombinant Rat IFN-γ 0 评论Submit a Review 产品详情 产品编号: 400-20 产品描述: IFN-γ is an acid-labile interferon produced by CD4 and CD8 T lymphocytes, as well as activated NK cells. IFN-γ receptors are present in most immune cells, which respond to IFN-γ signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-γ signaling in antigen-presenting cells, and antigen-recognizing B and T lymphocytes, regulates the antigen-specific phases of the immune response. Additionally, IFN-γ stimulates a number of lymphoid cell functions, including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Human IFN-γ is species-specific and is biologically active only in human and primate cells. Recombinant Rat IFN-γ is a 15.6 kDa protein containing 135 amino acid residues. Source: E.coli Synonyms: Immune Interferon, type II interferon, T cell interferon, MAF AA Sequence: MQGTLIESLE SLKNYFNSSS MDAMEGKSLL LDIWRNWQKD GNTKILESQI ISFYLRLFEV LKDNQAISNN ISVIESHLIT NFFSNSKAKK DAFMSIAKFE VNNPQIQHKA VNELIRVIHQ LSPESSLRKR KRSRC Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to inhibit the proliferation of mouse WEHI-279 cells. Calculated Molecular Weight: 15.6 kDa Accession Number: P01581 Gene ID: 25712 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Human, Mouse, Rat References PubMed SDS CoA 搜索 Product Line Country Of Origin: USA Not for human use. Research Interest COVID-19 艾滋病/HIV 血管生成/心血管 癌症 糖尿病/体重调节 免疫系统 神经生物学 干细胞&分化 过敏 移植 product.subtitle.recentcitations 第一作者 Kanai, R 标题 Interferon-γ enhances the therapeutic effect of mesenchymal stem cells on experimental renal fibrosis 文献引用 Scientific Reports; 11(1) pg850 PubMed Id 33441701 第一作者 Lewen, A 标题 Neuronal gamma oscillations and activity-dependent potassium transients remain regular after depletion of microglia in postnatal cortex tissue. 文献引用 Journal of Neuroscience Research; 98(10) pg1953-1967 PubMed Id 32638411 第一作者 Zogbi, C 标题 Beneficial effects of IL-4 and IL-6 on rat neonatal target cardiac cells. 文献引用 Scientific Reports; 10(1) pg12350 PubMed Id 32704142