Recombinant Rat IL-2 0 评论Submit a Review 产品详情 产品编号: 400-02 产品描述: IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes. Recombinant Rat IL-2 is a 15.3 kDa protein containing 134 amino acid residues. Source: E.coli Synonyms: T-cell growth factor (TCGF), Aldesleukin AA Sequence: MAPTSSPAKE TQQHLEQLLL DLQVLLRGID NYKNLKLPMM LTFKFYLPKQ ATELKHLQCL ENELGALQRV LDLTQSKSFH LEDAGNFISN IRVTVVKLKG SENKFECQFD DEPATVVEFL RRWIAIAQSI ISTM Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: The ED50 as determined by the dose-dependent stimulation of the proliferation of murine CTLL-2 cells is ≤ 0.4 ng/ml, corresponding to a specific activity of ≥ 2.5 x 106 units/mg. Calculated Molecular Weight: 15.3 kDa Accession Number: P17108 Gene ID: 116562 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Mouse, Rat References PubMed SDS CoA 搜索 Product Line Country Of Origin: USA Not for human use. Research Interest CAR T Cell COVID-19 艾滋病/HIV 癌症 细胞培养 糖尿病/体重调节 免疫系统 炎症 神经生物学 干细胞&分化 创伤修复 过敏 移植 product.subtitle.recentcitations 第一作者 Kim, B 标题 Tubulosine selectively inhibits JAK3 signalling by binding to the ATP-binding site of the kinase of JAK3 文献引用 Journal of Cellular and Molecular Medicine; 24(13) pg7427-7438 PubMed Id 32558259 第一作者 Ma, B 标题 Combining Exosomes Derived from Immature DCs with Donor Antigen-Specific Treg Cells Induces Tolerance in a Rat Liver Allograft Model. 文献引用 Scientific Reports; 6 pg32971 PubMed Id 27640806 第一作者 Hara, N 标题 Prevention of virus-induced type 1 diabetes with antibiotic therapy. 文献引用 Journal of immunology (Baltimore, Md. : 1950); 189(8) pg3805-14 PubMed Id 22988033