Recombinant Rat SDF-1α (CXCL12) 0 评论Submit a Review 产品详情 产品编号： 400-32A 产品描述： SDF-1α and β are stromal-derived, CXC chemokines that signal through the CXCR4 receptor. SDF-1α and β chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 proteins exert HIV-suppressive activity in cells expressing the CXCR4 receptor. Human and murine SDF-1 proteins act across species. SDF-1α and β contain the four highly conserved cysteine residues present in CXC chemokines. The mature SDF-1α protein is the result of alternative splicing of the SDF-1 gene and contains 68 amino acid residues. Recombinant Rat SDF-1α is a 7.9 kDa protein containing 68 amino acid residues. Source: E.coli AA Sequence: KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKSNNRQVC IDPKLKWIQE YLDKALNK Synonyms: Stromal-Cell Derived Factor-1, CXCL12, PBSF Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human peripheral blood monocytes using a concentration range of 50.0-100.0 ng/ml. Calculated Molecular Weight: 7.9 kDa Accession Number: Q9QZD1 Gene ID: 24772 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Human, Human + Rat, Rat References PubMed SDS CoA 搜索 Product Line Country Of Origin: USA Not for human use. Research Interest 艾滋病/HIV 化学趋化 免疫系统 炎症 神经生物学 干细胞&分化 创伤修复 product.subtitle.recentcitations 第一作者 Pouzol, L 标题 ACT-1004-1239, a first-in-class CXCR7 antagonist with both immunomodulatory and promyelinating effects for the treatment of inflammatory demyelinating diseases. 文献引用 FASEB journal : official publication of the Federation of American Societies for Experimental Biology; 35(3) pge21431 PubMed Id 33595155 第一作者 Jayasuriya, C T 标题 Human Cartilage-Derived Progenitors Resist Terminal Differentiation and Require CXCR4 Activation to Successfully Bridge Meniscus Tissue Tears. 文献引用 Stem cells (Dayton, Ohio); 37(1) pg102-114 PubMed Id 30358021 第一作者 Renko, O 标题 SDF1 gradient associates with the distribution of c-Kit+ cardiac cells in the heart. 文献引用 Scientific Reports; 8(1) pg1160 PubMed Id 29348441
