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Chemokines

Recombinant Human CXCL16

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Detalles del Producto

Nùmero de Catalogo 300-55
Descripcion
Recombinant Human CXCL16

CXCL16 is a member of the CXC chemokine family and signals through the CXCR6 receptor. CXCL16 may play a role in attracting lymphocyte subsets during inflammation and may facilitate certain immune responses. The chemokine domain of CXCL16 contains six cysteine residues, including the four highly conserved cysteine residues characteristic of CXC chemokines. The CXCL16 gene codes for a 273 amino acid polypeptide, which includes a 29 amino acid cytoplasmic domain and transmembrane sequence containing approximately 20 amino acids. The extracellular portion of CXCL16 contains a chemokines domain and an extended C-terminal "mucin-like stalk" sequence. The extracellular domain contains 89 amino acid residues (86 amino acid residues for the murine homolog). Recombinant Human CXCL16 is a 10.1 kDa protein containing 89 amino acid residues.

Source: E.coli

Synonyms: SRPSOX

AA Sequence: NEGSVTGSCY CGKRISSDSP PSVQFMNRLR KHLRAYHRCL YYTRFQLLSW SVCGGNKDPW VQELMSCLDL KECGHAYSGI VAHQKHLLP

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract activated lymphocytes using a concentration of 1.0-100.0 ng/ml.

Recombinant Human CXCL16 Biological Activity Graph

Calculated Molecular Weight: 10.1 kDa

Accession Number: Q9H2A7

Gene ID: 58191

Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

Primer autor
Du, Y
Titulo
Chemokines form nanoparticles with DNA and can superinduce TLR-driven immune inflammation.
Citar
The Journal of Experimental Medicine; 219(7)
PudMed id
Primer autor
Bouhaddou, M
Titulo
The Global Phosphorylation Landscape of SARS-CoV-2 Infection.
Citar
Cell; 182(3) pg685-712.e19
PudMed id
Primer autor
Blanco-Melo, D
Titulo
Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19.
Citar
Cell; 181(5) pg1036-1045.e9
PudMed id