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Growth Factors & Cytokines

Recombinant Human FGF-4

Detalles del Producto

Nùmero de Catalogo 100-31
Descripcion
Recombinant Human FGF-4

FGF-4 is a heparin-binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-4 signals through FGFR 1c, 2c, 3c, and 4. Recombinant Human FGF-4 is a 19.7 kDa protein consisting of 182 amino acid residues.

Source: E.coli

Synonyms: Fibroblast Growth Factor-4, HST-1, Transforming protein KS3, HBGF-4

AA Sequence: GRGGAAAPTA PNGTLEAELE RRWESLVALS LARLPVAAQP KEAAVQSGAG DYLLGIKRLR RLYCNVGIGF HLQALPDGRI GGAHADTRDS LLELSPVERG VVSIFGVASR FFVAMSSKGK LYGSPFFTDE CTFKEILLPN NYNAYESYKY PGMFIALSKN GKTKKGNRVS PTMKVTHFLP RL

Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by a cell proliferation assay using Balb/c 3T3 cells. The expected ED50 is ≤ 10 ng/ml, corresponding to a specific activity of ≥ 1 x 105 units/mg.

Recombinant Human FGF-4 Biological Activity Graph

Calculated Molecular Weight: 19.7 kDa

Accession Number: P08620

Gene ID: 2249

Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)

Note:

1mg will be provided as 2x500μg.

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

Primer autor
Capatina, N
Titulo
Elevated homocysteine activates unfolded protein responses and causes aberrant trophoblast differentiation and mouse blastocyst development.
Citar
Physiological Reports; 10(18) pge15467
PudMed id
Primer autor
Ryu, T Y
Titulo
Human gut-microbiome-derived propionate coordinates proteasomal degradation via HECTD2 upregulation to target EHMT2 in colorectal cancer.
Citar
The ISME Journal; 16(5) pg1205-1221
PudMed id
Primer autor
Muto, M
Titulo
Intersection of regulatory pathways controlling hemostasis and hemochorial placentation.
Citar
Proceedings of the National Academy of Sciences of the United States of America; 118(50)
PudMed id

product.subtitle.productreviews

Comentarios existentes
Great Product
We have been using this FGF-4 product to culture Trophoblast stem cells successfully. Always arrives quickly and works well.
De:  Alison | Fecha:  07/08/2020