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Growth Factors & Cytokines

Recombinant Human KGF (FGF-7)

Detalles del Producto

Nùmero de Catalogo 100-19
Descripcion
Recombinant Human KGF (FGF-7)

KGF (FGF-7) is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth, and the regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. KGF (FGF-7) is a mitogen factor specific for epithelial cells and keratinocytes. KGF (FGF-7) signals through FGFR 2b. KGF (FGF-7) plays a role in kidney and lung development, as well as in angiogenesis and wound healing. Recombinant Human KGF (FGF-7) is an 18.9 kDa protein consisting of 163 amino acid residues.

Source: E.coli

Synonyms: Keratinocyte Growth Factor, Fibroblast Growth Factor-7, HBGF-7

AA Sequence: CNDMTPEQMA TNVNCSSPER HTRSYDYMEG GDIRVRRLFC RTQWYLRIDK RGKVKGTQEM KNNYNIMEIR TVAVGIVAIK GVESEFYLAM NKEGKLYAKK ECNEDCNFKE LILENHYNTY ASAKWTHNGG EMFVALNQKG IPVRGKKTKK EQKTAHFLPM AIT

Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by a cell proliferation assay using 4MBr-5 cells. The expected ED50 for this effect is 0.1-15 ng/ml.

This product has been tested against the WHO standard. International Unit information can be found here.

Recombinant Human KGF (FGF-7) WHO Comparison Graph Recombinant Human KGF (FGF-7) Biological Activity Graph

Calculated Molecular Weight: 18.9 kDa

Accession Number: P21781

Gene ID: 2252

Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

Primer autor
Tanaka, J
Titulo
Human induced pluripotent stem cell-derived salivary gland organoids model SARS-CoV-2 infection and replication.
Citar
Nature Cell Biology; 24(11) pg1595-1605
PudMed id
Primer autor
Ngan, S Y
Titulo
Stage-Specific Generation of Human Pluripotent Stem Cell Derived Lung Models to Measure CFTR Function.
Citar
Current Protocols; 2(1) pge341
PudMed id
Primer autor
van der Vaart, J
Titulo
Modelling of primary ciliary dyskinesia using patient-derived airway organoids.
Citar
EMBO reports; 22(12) pge52058
PudMed id

product.subtitle.productreviews

Comentarios existentes
It works well
It works well both in human and mouse organoid culture.
De:  Eun Joo | Fecha:  08/07/2020
Excellent quality
We utilize FGF7 as part of lung cancer organoid media for cancers which do not have EGFR mutations. We have had great results and excellent service.
De:  Dora | Fecha:  24/07/2020
Great for organoids!
We use this in two types patient tumor organoid media and have wonderful results in each.
De:  Julie-Ann | Fecha:  03/08/2021