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Chemokines

Recombinant Human MEC (CCL28)

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Detalles del Producto

Nùmero de Catalogo 300-57
Descripcion
Recombinant Human MEC (CCL28)

MEC is a secreted CC chemokine expressed primarily by epithelial cells of the bronchioles, salivary gland, mammary gland and colon. MEC signals through the CCR10 receptor, and chemoattracts resting CD4, CD8T-cells and eosinophils. MEC contains six cysteines, including the four highly conserved cysteine residues present in CC chemokines. Recombinant Human MEC is a 12.3 kDa protein containing 108 amino acid residues.

Source: E.coli

Synonyms: Mucosae-associated Epithelial Chemokine, CCL28, CCK-1

AA Sequence: SEAILPIASS CCTEVSHHIS RRLLERVNMC RIQRADGDCD LAAVILHVKR RRICVSPHNH TVKQWMKVQA AKKNGKGNVC HRKKHHGKRN SNRAHQGKHE TYGHKTPY

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract human lymphocytes using a concentration range of 1.0-10.0 ng/ml.

Recombinant Human MEC (CCL28) Biological Activity Graph

Calculated Molecular Weight: 12.3 kDa

Accession Number: Q9NRJ3

Gene ID: 56477

Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

Primer autor
Fu, Y
Titulo
CD27-CD38+ B cells accumulated in early HIV infection exhibit transitional profile and promote HIV disease progression.
Citar
Cell Reports; 36(2) pg109344
PudMed id
Primer autor
Park, J
Titulo
CCL28-induced RARβ expression inhibits oral squamous cell carcinoma bone invasion.
Citar
The Journal of Clinical Investigation; 129(12) pg5381-5399
PudMed id
Primer autor
Buskermolen, J K
Titulo
Stimulation of oral fibroblast chemokine receptors identifies CCR3 and CCR4 as potential wound healing targets.
Citar
Journal of Cellular Physiology; 232(11) pg2996-3005
PudMed id