Recombinant Human MIG (CXCL9) 0 ComentariosSubmit a Review Detalles del Producto Nùmero de Catalogo 300-26 Descripcion MIG, a CXC chemokine, is produced by IFN-γ stimulated monocytes, macrophages and endothelial cells. It signals through the CXCR3 receptor. MIG selectively chemoattracts Th1 lymphocytes, and also exerts other activities, including inhibition of tumor growth, angiogenesis, and inhibition of colony formation of hematopoietic progenitors. Human MIG is active on murine cells. Recombinant Human MIG is an 11.7 kDa protein containing 103 amino acid residues, including the four highly conserved cysteine residues present in CXC chemokines. Source: E.coli Synonyms: Monokine Induced by Interferon-gamma, CXCL9 AA Sequence: TPVVRKGRCS CISTNQGTIH LQSLKDLKQF APSPSCEKIE IIATLKNGVQ TCLNPDSADV KELIKKWEKQ VSQKKKQKNG KKHQKKKVLK VRKSQRSRQK KTT Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human peripheral blood T lymphocytes using a concentration range of 10.0-100.0 ng/ml. Calculated Molecular Weight: 11.7 kDa Accession Number: Q07325 Gene ID: 4283 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Bacteria, Human, Mouse, References PubMed SDS Búsqueda del CoA Product Line Country Of Origin: USA Not for human use. Research Interest COVID-19 Angiogenesis/Cardiovascular Chemotaxis Immune System Inflammation Wound Healing Transplantation product.subtitle.recentcitations Primer autor Du, Y Titulo Chemokines form nanoparticles with DNA and can superinduce TLR-driven immune inflammation. Citar The Journal of Experimental Medicine; 219(7) PudMed id 35640018 Primer autor Poosti, F Titulo Inhibition of renal fibrosis with a human CXCL9-derived glycosaminoglycan-binding peptide. Citar Clinical & translational immunology; 11(2) pge1370 PudMed id 35140938 Primer autor Gurusamy, M Titulo G-protein-coupled receptor P2Y10 facilitates chemokine-induced CD4 T cell migration through autocrine/paracrine mediators. Citar Nature Communications; 12(1) pg6798 PudMed id 34815397
