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Chemokines

Recombinant Human MIP-3α (CCL20)

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Detalles del Producto

Nùmero de Catalogo 300-29A
Descripcion
Recombinant Human MIP-3α (CCL20)

MIP-3α is a CC chemokine, expressed in the liver, lymph nodes, appendix, PBL and lungs that can signal through the CCR6 receptor. MIP-3α is chemotactic towards lymphocytes and dendritic cells. Additionally, it promotes the adhesion of memory CD4+ T cells, and inhibits colony formation of bone marrow myeloid immature progenitors. Recombinant Human MIP-3α is an 8.0 kDa protein containing 70 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

Source: E.coli

Synonyms: Macrophage Inflammatory Protein-3α, CCL20, LARC, Exodus-1

AA Sequence: ASNFDCCLGY TDRILHPKFI VGFTRQLANE GCDINAIIFH TKKKLSVCAN PKQTWVKYIV RLLSKKVKNM

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract human T cells using a concentration of 10.0-50.0 ng/ml.

Calculated Molecular Weight: 8 kDa

Accession Number: P78556

Gene ID: 6364

Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

Primer autor
Nguyen, D X
Titulo
Regulatory T cells enhance Th17 migration in psoriatic arthritis which is reversed by anti-TNF.
Citar
Iscience; 24(9) pg102973
PudMed id
Primer autor
Bouhaddou, M
Titulo
The Global Phosphorylation Landscape of SARS-CoV-2 Infection.
Citar
Cell; 182(3) pg685-712.e19
PudMed id
Primer autor
Lee, A W
Titulo
A knottin scaffold directs the CXC-chemokine-binding specificity of tick evasins.
Citar
The Journal of Biological Chemistry; 294(29) pg11199-11212
PudMed id