Recombinant Murine FGF-acidic 0 ComentariosSubmit a Review Detalles del Producto Nùmero de Catalogo 450-33A Descripcion FGF-acidic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-acidic is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. FGF-acidic has the ability to signal through all the FGF receptors. Recombinant Murine FGF-acidic is a 15.9 kDa protein consisting of 141 amino acid residues. Source: E.coli Synonyms: Fibroblast Growth Factor-acidic, FGF-1, HBGF-1, ECGF-beta AA Sequence: MFNLPLGNYK KPKLLYCSNG GHFLRILPDG TVDGTRDRSD QHIQLQLSAE SAGEVYIKGT ETGQYLAMDT EGLLYGSQTP NEECLFLERL EENHYNTYTS KKHAEKNWFV GLKKNGSCKR GPRTHYGQKA ILFLPLPVSS D Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by a cell proliferation assay using Balb/c 3T3 cells. The expected ED50 is ≤ 0.2 ng/ml in the presence of 10 µg/ml heparin, corresponding to a specific activity of ≥ 5 x 106 units/mg. Calculated Molecular Weight: 15.9 kDa Accession Number: P61148 Gene ID: 14164 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Human, Mouse, References PubMed SDS Búsqueda del CoA Product Line Country Of Origin: USA Not for human use. Research Interest Angiogenesis/Cardiovascular Bone, Skeletal, Cartilage Cancer Cell Culture FGF Superfamily Immune System Inflammation Neurobiology Stem Cells & Differentiation Wound Healing product.subtitle.recentcitations Primer autor Guccini, I Titulo Senescence Reprogramming by TIMP1 Deficiency Promotes Prostate Cancer Metastasis. Citar Cancer Cell; 39(1) pg68-82.e9 PudMed id 33186519 Primer autor Westphal, S Titulo Fibroblast growth factor 8b induces uncoupling protein 1 expression in epididymal white preadipocytes. Citar Scientific Reports; 9(1) pg8470 PudMed id 31186471 Primer autor Ishihara, J Titulo Laminin heparin-binding peptides bind to several growth factors and enhance diabetic wound healing. Citar Nature Communications; 9(1) pg2163 PudMed id 29867149