Animal-Free Recombinant Murine IL-2 1 ComentariosSubmit a Review Detalles del Producto Nùmero de Catalogo AF-212-12 Descripcion IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes. Recombinant Murine IL-2 is a 17.2 kDa protein containing 148 amino acid residues. Manufactured using all Animal-Free reagents. Source: E.coli Synonyms: T-cell growth factor, (TCGF), Aldesleukin AA Sequence: PTSSSTSSST AEAQQQQQQQ QQQQQHLEQL LMDLQELLSR MENYRNLKLP RMLTFKFYLP KQATELKDLQ CLEDELGPLR HVLDLTQSKS FQLEDAENFI SNIRVTVVKL KGSDNTFECQ FDDESATVVD FLRRWIAFCQ SIISTSPQ Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to stimulate the proliferation of mouse CTLL-2 cells. The expected ED50 is ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 106 units/mg. This product has been tested against the WHO standard. International Unit information can be found here. Calculated Molecular Weight: 17.2 kDa Accession Number: P04351 Gene ID: 16183 Endotoxin: Endotoxin level is < 0.01 ng/ug of protein (< 0.1 EU/ug) crossreactivity: Mouse References PubMed SDS Búsqueda del CoA Product Line Country Of Origin: USA Not for human use. Research Interest CAR T Cell COVID-19 AIDS/HIV Cancer Cell Culture Diabetes/Weight Regulation Immune System Inflammation Neurobiology Stem Cells & Differentiation Wound Healing Allergy Transplantation product.subtitle.recentcitations Primer autor Fiancette, R Titulo Reciprocal transcription factor networks govern tissue-resident ILC3 subset function and identity Citar Nature Immunology; 22(10) pg1245-1255 PudMed id 34556884 Primer autor Cardoso, F Titulo Neuro-mesenchymal units control ILC2 and obesity via a brain-adipose circuit Citar Nature; 597(7876) pg410-414 PudMed id 34408322 Primer autor Cui, J Titulo IL-4 inhibits regulatory T cells differentiation by HDAC9-mediated epigenetic regulation. Citar Cell Death & Disease; 12(6) pg501 PudMed id 34006836 product.subtitle.productreviews Comentarios existentes Best cytokine of its kind Have used this cytokine for T cell expansion. Very reliable and efficient. Gives good results every time. De: Vineet | Fecha: 26/08/2020 × Best cytokine of its kind Have used this cytokine for T cell expansion. Very reliable and efficient. Gives good results every time. De: Vineet | Fecha: 26/08/2020 Close