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Chemokines

Recombinant Rat GRO/KC (CXCL1)

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Detalles del Producto

Nùmero de Catalogo 400-10
Descripcion
Recombinant Rat GRO/KC (CXCL1)

All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant Rat GRO/KC is a 7.8 kDa protein consisting of 72 amino acids, including the 'ELR' motif common to the CXC chemokine family that binds to CXCR1 or CXCR2.

Source: E.coli

Synonyms: MGSAα, CXCL1, NAP-3, GRO1, GRO/MGSA (human), KC (murine), CINC (rat)

AA Sequence: APVANELRCQ CLQTVAGIHF KNIQSLKVMP PGPHCTQTEV IATLKNGREA CLDPEAPMVQ KIVQKMLKGV PK

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract rat neutrophils using a concentration range of 10.0-100.0 ng/ml.

Recombinant Rat GRO/KC (CXCL1) Biological Activity Graph

Calculated Molecular Weight: 7.8 kDa

Accession Number: P14095

Gene ID: 81503

Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)

Note:

1mg will be provided as 2x500μg.

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

Primer autor
Cai, Y
Titulo
Immunological characterization of HM5023507, an orally active PI3Kδ/γ inhibitor.
Citar
Pharmacology Research and Perspectives; 8(1) pge00559
PudMed id
Primer autor
Boespflug, N D
Titulo
ATF3 is a novel regulator of mouse neutrophil migration.
Citar
Blood; 123(13) pg2084-93
PudMed id
Primer autor
Abu-Taha, M
Titulo
Menopause and ovariectomy cause a low grade of systemic inflammation that may be prevented by chronic treatment with low doses of estrogen or losartan.
Citar
Journal of immunology (Baltimore, Md. : 1950); 183(2) pg1393-402
PudMed id